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Insulin Aspart Prot & Aspart

Insulin Aspart Prot & Asp FlexPen is a combination of insulin aspart, a rapid-acting insulin, and insulin aspart protamine, an intermediate-acting insulin. This dual formulation is designed to provide both mealtime insulin coverage and a longer-lasting effect for better overall blood sugar control. The FlexPen allows for convenient and precise dosing for patients managing their diabetes.



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Frequently Asked Questions

How long does it take for Insulin Aspart Prot & Asp FlexPen to start working?
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Insulin aspart typically starts to lower blood glucose levels within 15 minutes after injection, while the protamine component provides a more prolonged effect.

Can I take Insulin Aspart Prot & Asp FlexPen with other medications?
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Always consult your healthcare provider before combining Insulin Aspart Prot & Asp FlexPen with other medications, especially other insulin or oral antidiabetic agents.

What should I do if I miss a dose of Insulin Aspart Prot & Asp?
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If you miss a dose, take it as soon as you remember. If it’s close to the time for your next scheduled dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

Is it safe to use Insulin Aspart Prot & Asp FlexPen during pregnancy?
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Insulin Aspart Prot & Asp FlexPen may be used during pregnancy if clearly needed, but the risks and benefits should be discussed with a healthcare provider.

Can Insulin Aspart Prot & Asp FlexPen cause weight gain?
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Weight gain can occur as a side effect of insulin therapy, so patients should monitor their weight and discuss any concerns with their healthcare provider.

Comprehensive Drug Guide

How Does Insulin Aspart Prot & Aspart Work?

  • Insulin Aspart works quickly to lower blood glucose levels by facilitating the uptake of glucose into cells and inhibiting hepatic glucose production. It is effective for managing blood sugar spikes after meals.
  • Insulin Aspart Protamine provides a more sustained release of insulin, helping to maintain blood glucose levels between meals and overnight.


Common Dosages

  • Pre-filled pen: Contains a mix of insulin aspart and insulin aspart protamine, usually in a ratio that provides both rapid and intermediate-acting effects.

Typical Dosing

  • The dosing is individualized based on blood glucose levels, dietary intake, and physical activity. It is usually administered subcutaneously before meals.
  • The specific dosing schedule will depend on the patient's needs, with adjustments made according to their response to treatment.


Typical Dosing

FDA Approved Indications

  • Management of diabetes mellitus in adults and children, specifically for controlling blood glucose levels during meals and throughout the day.


Who Shouldn't Take Insulin Aspart Prot & Aspart?

  • Known hypersensitivity to insulin aspart, insulin aspart protamine, or any components of the formulation
  • Episodes of hypoglycemia (low blood sugar)


Advice From The Pharmacist

  • Patients should be instructed on the proper technique for using the FlexPen to ensure effective delivery of the medication.
  • Regular monitoring of blood glucose levels is essential to evaluate the effectiveness of the insulin regimen and to make necessary dose adjustments.
  • Store unused pens in the refrigerator and allow them to reach room temperature before use.


Side Effects of Insulin Aspart Prot & Aspart

Common Side Effects

  • Hypoglycemia (low blood sugar)
  • Injection site reactions (redness, swelling, pain)
  • Weight gain


Uncommon/Severe Side Effects

  • Severe allergic reactions (anaphylaxis)
  • Hypoglycemic unawareness (difficulty recognizing symptoms of low blood sugar)


Risks and Warnings of Insulin Aspart Prot & Aspart

  • Hypoglycemia: Patients must be educated on recognizing the symptoms of low blood sugar and how to treat it promptly.
  • Allergic Reactions: Monitor for signs of severe allergic reactions and report any such symptoms to a healthcare provider.
  • Dosing Adjustments: Doses may need to be adjusted based on changes in diet, exercise, or illness.


Interactions with Insulin Aspart Prot & Aspart

Common Drug Interactions

  • Other Antidiabetic Medications: Careful monitoring is required when using Insulin Aspart Prot & Asp FlexPen with other diabetes medications to avoid hypoglycemia.
  • Beta-Blockers: These medications may mask the symptoms of hypoglycemia.
  • Alcohol: Should be consumed with caution, as it can increase the risk of hypoglycemia.


Alternatives to Insulin Aspart Prot & Aspart

  • Insulin Aspart U-100: A standard rapid-acting formulation for patients who do not require a mixed product.
  • Insulin Lispro: Another rapid-acting insulin for managing postprandial blood glucose levels.
  • Basal-bolus regimens: Using long-acting insulin combined with rapid-acting insulin for more precise control.