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Imvexxy Maintenance Pack

Imvexxy is a bioidentical hormone replacement therapy that contains estradiol, a form of estrogen. It is specifically designed to treat symptoms associated with vulvar and vaginal atrophy due to menopause, such as dryness, irritation, and painful intercourse. The Imvexxy Maintenance Pack allows for ongoing treatment to help alleviate these symptoms by restoring estrogen levels in the vaginal area.



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Frequently Asked Questions

How long does it take for Imvexxy to start working?
Open FAQClose FAQ

Patients may start to notice improvements in symptoms within a few days to weeks of starting treatment, but it may take longer for full effects.

Can I use Imvexxy if I have a history of breast cancer?
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Imvexxy should be used with caution in individuals with a history of breast cancer, and patients should discuss their medical history with their healthcare provider before starting treatment.

What should I do if I miss a dose of Imvexxy?
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If you miss a dose, use it as soon as you remember. If it’s almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double up doses.

Is it safe to use Imvexxy during pregnancy?
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Imvexxy is not indicated for use during pregnancy and should only be used in women who are postmenopausal.

Can I use Imvexxy while breastfeeding?
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Estrogen therapy is generally not recommended during breastfeeding. Consult your healthcare provider for personalized advice based on your situation.

Comprehensive Drug Guide

How Does Imvexxy Maintenance Pack Work?

Imvexxy works by delivering estradiol directly to the vaginal tissues, which helps to restore moisture and elasticity. By acting on estrogen receptors in the vaginal and vulvar tissues, it alleviates symptoms of dryness and atrophy, improving overall vaginal health and comfort.



Common Dosages

  • Inserts: Typically available in doses of 10 mcg and 25 mcg of estradiol.

Typical Dosing

  • The usual recommended dosing is one insert administered vaginally once daily for a specified period, followed by a maintenance dose as directed by a healthcare provider, typically reduced to two or three times a week.


Typical Dosing

FDA Approved Indications

  • Moderate to severe vulvar and vaginal atrophy due to menopause.


Who Shouldn't Take Imvexxy Maintenance Pack?

  • Known hypersensitivity to estradiol or any components of the formulation
  • Undiagnosed abnormal genital bleeding
  • History of estrogen-dependent tumors
  • Active or recent thromboembolic disorders (e.g., deep vein thrombosis, pulmonary embolism)


Advice From The Pharmacist

  • Imvexxy should be used according to the prescribed regimen, and patients should follow their healthcare provider's instructions regarding dosing and duration of use.
  • Patients should be informed about the proper method of inserting the softgel insert for maximum effectiveness.
  • Regular follow-up appointments are recommended to monitor the treatment's effectiveness and any potential side effects.


Side Effects of Imvexxy Maintenance Pack

Common Side Effects

  • Vaginal irritation
  • Discharge
  • Headache
  • Nausea


Uncommon/Severe Side Effects

  • Signs of blood clots (e.g., sudden leg swelling, chest pain, shortness of breath)
  • Severe allergic reactions (anaphylaxis)


Risks and Warnings of Imvexxy Maintenance Pack

  • Cardiovascular Risks: Estrogen therapy can increase the risk of thromboembolic events, particularly in women with a history of such conditions.
  • Breast Cancer Risk: Long-term use of estrogen therapy may increase the risk of breast cancer; patients should discuss their individual risk factors with their healthcare provider.
  • Monitor Symptoms: Patients should report any unusual vaginal bleeding or symptoms to their healthcare provider immediately.


Interactions with Imvexxy Maintenance Pack

Common Drug Interactions

  • Anticoagulants: Estradiol may enhance the effects of blood thinners, requiring careful monitoring and potential dosage adjustments.
  • Certain Anticonvulsants: Some medications may decrease the effectiveness of estradiol; consult your healthcare provider for specific interactions.


Alternatives to Imvexxy Maintenance Pack

  • Vaginal estrogen creams: Alternatives that also provide localized estrogen therapy.
  • Ospemifene (Osphena): An oral medication used to treat dyspareunia (painful intercourse) due to menopausal changes.
  • Non-hormonal vaginal moisturizers: Available over-the-counter options for relief of vaginal dryness.