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Hyosyne
Hyosyne, also known as Hyoscyamine, is an anticholinergic medication. It is used to treat a variety of gastrointestinal issues such as cramps, ulcers, and irritable bowel syndrome due to its ability to reduce the activity of certain muscles and glands in the stomach and intestines. Common side effects include dizziness, drowsiness, blurred vision, and dry mouth.
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Frequently Asked Questions
Can I just stop taking Hyosyne if I feel better?
Don't stop taking Hyosyne without consulting with your healthcare provider as it might cause withdrawal symptoms.
How long does it take for Hyosyne to start working?
You'll probably start to notice the effects around 30 minutes after taking it.
What should I do if I miss a dose?
If it is near the time for the next dose, skip the missed one and go back to your regular dosing schedule. Don't double up.
Comprehensive Drug Guide
How Does Hyosyne Work?
Hyosyne, as an anticholinergic agent, inhibits the actions of acetylcholine at postganglionic nerve endings, resulting in decreased motility and muscle tone, secretions, and acidity in the stomach and bowel.
What is Hyosyne Used For?
FDA indications: Hyosyne is used to treat several stomach/intestinal problems, such as cramps and irritable bowel syndrome. It's also used to treat other conditions such as control of the bladder, symptoms of Parkinson's disease, and control of secretions in certain surgical procedures.
Offlabel uses: Sometimes, it is used to relieve pain related to kidney stones or gallstones and manage the symptoms of alcohol withdrawal.
Common Dosages
Tablets: 0.125mg, 0.25mg
Typical Dosing
FDA Approved Indications
- Dosage will depend on the condition being treated and the patient's response, but typically ranges from 0.125mg to 0.25mg taken every four hours.
- Do not exceed 1.5mg in 24 hours.
Who Shouldn't Take Hyosyne?
- Those with a history of severe hypersensitivity reactions to hyoscyamine or related drugs.
- Patients with narrowangle glaucoma.
- Patients with obstructive uropathy or obstructive disease of the gastrointestinal tract.
- Patients with unstable cardiovascular status in acute hemorrhaging.
- Patients with myasthenia gravis.
- Patients with acute intermittent porphyria.
- Also, if pregnant or planning a pregnancy, consult your healthcare provider if Hyosyne is essential to your treatment.
Advice From The Pharmacist
- It is best to take Hyosyne on an empty stomach.
- Hyosyne can make you dizzy or drowsy, do not drive, use machinery,
- Limit your alcohol intake as it can make the drowsiness worse.
- Hyosyne can make you sweat less, and you may be more prone to heat stroke. Avoid strenuous activities in hot weather.
Side Effects of Hyosyne
Common Side Effects
- You may feel dizzy or drowsy.
- You may have blurred vision.
- Dry mouth is also common.
- You might feel constipated
Uncommon/Severe Side Effects
- Uncommon side effects:
- You might feel nervous or have trouble sleeping.
- Your heart rate may be increased.
- Rare side effects:
- You might experience a rash or itching.
- Difficulty urinating could happen.
- Severe side effects:
- Chest pain, shortness of breath, or fainting are serious and require medical attention immediately.
- If you experience mood changes or mental changes like confusion or hallucinations, seek immediate medical help.
Risks and Warnings of Hyosyne
- Hyosyne should be used with caution if you have a history of heart disease, high blood pressure, liver disease, kidney disease, or an overactive thyroid.
- It should also be used carefully if you have a history of diseases such as glaucoma, myasthenia gravis, or urinary retention.
Interactions with Hyosyne
Common Drug Interactions
- Antihistamines or MAO inhibitors
- Medications for sleep, anxiety, or muscle relaxation
- Medications for depression, like amitriptyline
- Other anticholinergic drugs, like atropine
Alternatives to Hyosyne
- Dicyclomine
- Atropine
- Scopolamine
- Methscopolamine
- Propantheline
