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Hyoscyamine Sulfate ER
Hyoscyamine Sulfate ER (extended-release) is an anticholinergic medication used primarily to treat gastrointestinal disorders, including irritable bowel syndrome (IBS) and conditions that involve muscle spasms in the gastrointestinal tract. The extended-release formulation allows for a gradual release of the medication over time, providing prolonged symptom relief.
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Frequently Asked Questions
How long does it take for Hyoscyamine Sulfate ER to start working?
Patients may begin to feel relief from symptoms within 30 minutes of administration.
Can I take Hyoscyamine Sulfate ER with other medications?
Always consult your healthcare provider before combining Hyoscyamine with other medications, especially other anticholinergics or drugs affecting gastrointestinal motility.
What should I do if I miss a dose?
If you miss a dose, take it as soon as you remember unless it is close to your next scheduled dose. Do not double the dose.
Is it safe to use Hyoscyamine Sulfate ER during pregnancy?
Hyoscyamine should be used during pregnancy only if clearly needed, and the risks and benefits should be discussed with a healthcare provider.
Can Hyoscyamine Sulfate ER cause weight gain?
Weight gain is not a common side effect of Hyoscyamine; however, any significant changes in weight should be discussed with a healthcare provider.
Comprehensive Drug Guide
How Does Hyoscyamine Sulfate ER Work?
Hyoscyamine Sulfate ER works by blocking the action of acetylcholine, a neurotransmitter that stimulates muscle contractions in the gastrointestinal tract. By inhibiting this action, it helps to relax smooth muscle, reduce spasms, and alleviate abdominal pain associated with gastrointestinal disorders.
Common Dosages
- Extended-release tablets: Typically 0.375 mg.
Typical Dosing
- The usual starting dose for adults is 0.375 mg to 0.75 mg taken orally, usually twice daily. The dose may be adjusted based on individual response and tolerability.
Typical Dosing
FDA Approved Indications
- Irritable bowel syndrome (IBS)
- Peptic ulcers
- Gastrointestinal spasm
Who Shouldn't Take Hyoscyamine Sulfate ER?
- Known hypersensitivity to hyoscyamine or any components of the formulation
- Glaucoma
- Myasthenia gravis
- Severe ulcerative colitis
- Tachycardia
Advice From The Pharmacist
- Hyoscyamine should be taken as directed, and patients should be advised to follow a regular dosing schedule.
- Patients should be instructed to maintain hydration, as anticholinergic medications can cause dry mouth and decreased sweating.
- Monitor for signs of side effects, especially dizziness or confusion, and report any severe symptoms to a healthcare provider.
Side Effects of Hyoscyamine Sulfate ER
Common Side Effects
- Dry mouth
- Dizziness
- Blurred vision
- Constipation
- Urinary retention
Uncommon/Severe Side Effects
- Severe allergic reactions (anaphylaxis)
- Tachycardia (increased heart rate)
- Confusion or hallucinations, particularly in older adults
Risks and Warnings of Hyoscyamine Sulfate ER
- Caution in Elderly Patients: Older adults may be more sensitive to the effects of hyoscyamine, leading to an increased risk of confusion and falls.
- Anticholinergic Effects: Monitor for signs of excessive anticholinergic effects, such as severe dryness, confusion, or difficulty urinating.
Interactions with Hyoscyamine Sulfate ER
Common Drug Interactions
- Other Anticholinergic Drugs: Use with caution, as this can increase the risk of side effects.
- Medications that affect gastrointestinal motility: Such as opioids, may have additive effects.
Alternatives to Hyoscyamine Sulfate ER
- Dicyclomine: Another anticholinergic used for gastrointestinal spasm.
- Peppermint oil: An herbal remedy that may help with IBS symptoms.
- Probiotics: Supplements that may help improve gut health and alleviate IBS symptoms.
