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HYDROmorphone HCl PF
Hydromorphone HCl PF (preservative-free) is a potent opioid analgesic used for the relief of moderate to severe pain. It is particularly useful in situations where patients require a strong analgesic effect, such as post-operative pain or pain associated with cancer. The preservative-free formulation is designed for patients with sensitivities or allergies to preservatives.
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Frequently Asked Questions
How quickly does Hydromorphone HCl PF provide pain relief?
Pain relief is typically experienced within 15 to 30 minutes of administration, particularly when given intravenously.
Can I take Hydromorphone HCl PF while pregnant?
Consult your healthcare provider for guidance, as the use during pregnancy should be evaluated based on risks and benefits.
What should I do if I miss a dose?
If you miss a dose while using a continuous infusion or scheduled dosing, contact your healthcare provider for instructions.
Are there any specific storage instructions for Hydromorphone HCl PF?
Store at room temperature, away from moisture and light. Keep out of reach of children.
Is Hydromorphone HCl PF safe for long-term use?
Long-term use should be monitored by a healthcare provider to manage risks, including dependence and potential adverse effects.
Comprehensive Drug Guide
How Does HYDROmorphone HCl PF Work?
Hydromorphone works by binding to opioid receptors in the central nervous system, primarily the mu-opioid receptors. This action alters the perception of pain and emotional response to pain, leading to effective pain relief.
Common Dosages
- Injectable solution: Common concentrations include 1 mg/mL, 2 mg/mL, or higher concentrations for specific medical needs.
Typical Dosing
The typical dosing for Hydromorphone HCl PF is:
- For Pain Management: Dosing is individualized; the initial dose for opioid-naive patients is typically 0.2 to 1 mg administered slowly via intravenous injection every 2 to 3 hours as needed.
Typical Dosing
FDA Approved Indications
- Management of moderate to severe pain in patients requiring opioid analgesia.
Who Shouldn't Take HYDROmorphone HCl PF?
- Hypersensitivity: Known hypersensitivity to hydromorphone or any components of the formulation.
- Severe Respiratory Depression: Should not be used in patients with significant respiratory issues or asthma.
- History of Substance Abuse: Use with caution in patients with a history of substance use disorder.
Advice From The Pharmacist
- How to Use: Hydromorphone should be administered by a qualified healthcare provider, typically via intravenous or intramuscular injection.
- Monitor for Side Effects: Patients should be monitored for signs of respiratory depression, sedation, and potential allergic reactions.
- Avoid Alcohol: Alcohol can increase the risk of serious side effects and should be avoided while taking this medication.
Side Effects of HYDROmorphone HCl PF
Common Side Effects
- Drowsiness
- Dizziness
- Constipation
- Nausea
Uncommon/Severe Side Effects
- Respiratory depression: Symptoms like slow or difficult breathing.
- Severe allergic reactions: Such as rash, itching, or difficulty breathing.
Risks and Warnings of HYDROmorphone HCl PF
- Caution with Other CNS Depressants: Concurrent use with other central nervous system depressants may enhance sedation and respiratory depression.
- Dependence and Withdrawal: Long-term use can lead to physical dependence and withdrawal symptoms upon discontinuation.
Interactions with HYDROmorphone HCl PF
Common Drug Interactions
- Drug Interactions: Hydromorphone HCl PF may interact with other medications that affect the central nervous system, including sedatives and certain antidepressants. Always inform your healthcare provider about all medications you are taking.
Alternatives to HYDROmorphone HCl PF
- Other Opioid Analgesics: Such as morphine or oxycodone for moderate to severe pain management.
- Non-Opioid Pain Relievers: Such as acetaminophen or NSAIDs for less severe pain.
