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Hydrocortisone-Acetic Acid

Hydrocortisone-Acetic Acid is a combination medication that includes hydrocortisone, a corticosteroid, and acetic acid, an antiseptic. This formulation is typically used to treat various inflammatory conditions and infections of the ear, such as otitis externa (swimmer's ear) and other conditions where inflammation and infection occur. Hydrocortisone helps reduce inflammation, while acetic acid helps combat bacterial growth.



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Frequently Asked Questions

How long does it take for Hydrocortisone-Acetic Acid to start working?
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Patients may begin to notice relief within a few days of starting treatment, but full effects may take up to a week.

Can I use Hydrocortisone-Acetic Acid with other medications?
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Always consult your healthcare provider before combining Hydrocortisone-Acetic Acid with other ear medications.

What should I do if I miss a dose?
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If you miss a dose, administer it as soon as you remember. If it’s close to the time for the next dose, skip the missed dose and continue with your regular schedule.

Is it safe to use Hydrocortisone-Acetic Acid during pregnancy?
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Hydrocortisone-Acetic Acid should be used during pregnancy only if clearly needed, and the risks and benefits should be discussed with a healthcare provider.

Can Hydrocortisone-Acetic Acid cause any side effects?
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Yes, some common side effects include ear discomfort and itching. If any severe side effects occur, such as allergic reactions, seek medical attention immediately.

Comprehensive Drug Guide

How Does Hydrocortisone-Acetic Acid Work?

  • Hydrocortisone works by inhibiting the inflammatory response, reducing swelling, redness, and pain associated with inflammation.
  • Acetic acid acts as an antiseptic, creating an environment that is inhospitable for certain bacteria and fungi, thereby helping to prevent or treat infections.


What is Hydrocortisone-Acetic Acid Used For?

  • Inflammation and infection of the ear, such as otitis externa.


Common Dosages

  • Ear drops: Typically containing 1% hydrocortisone and 2% acetic acid.

Typical Dosing

  • The usual dosing regimen involves instilling 4-5 drops into the affected ear 3 to 4 times daily, or as directed by a healthcare provider. The drops should be administered while lying down to allow for proper penetration.


Typical Dosing

FDA Approved Indications

  • Known hypersensitivity to hydrocortisone, acetic acid, or any components of the formulation
  • Viral infections of the ear (e.g., herpes simplex)
  • Fungal infections of the ear


Who Shouldn't Take Hydrocortisone-Acetic Acid?

  • Known hypersensitivity to hydrocortisone, acetic acid, or any components of the formulation
  • Viral infections of the ear (e.g., herpes simplex)
  • Fungal infections of the ear


Advice From The Pharmacist

  • Patients should be instructed on the proper technique for administering ear drops, including how to position the head for optimal delivery.
  • Advise patients to avoid getting water in the ear while using this medication, as moisture can exacerbate infections.
  • Encourage patients to complete the full course of treatment even if symptoms improve before finishing the medication.


Side Effects of Hydrocortisone-Acetic Acid

Common Side Effects

  • Ear discomfort or irritation
  • Itching in the ear
  • Sensation of fullness in the ear


Uncommon/Severe Side Effects

  • Severe allergic reactions (anaphylaxis)
  • Worsening of infections


Risks and Warnings of Hydrocortisone-Acetic Acid

  • Infection Risk: Monitor for signs of worsening infection or allergic reaction. If symptoms do not improve or worsen, patients should seek medical advice.
  • Prolonged Use: Long-term use of corticosteroids can lead to potential systemic absorption and side effects; use should be limited to the prescribed duration.

Interactions with Hydrocortisone-Acetic Acid

Common Drug Interactions

  • Other Ear Medications: Caution is advised when using other ear medications concurrently; they should be spaced apart to avoid interference.
  • Systemic Corticosteroids: While there are no direct interactions, be aware of the total corticosteroid exposure in patients using both systemic and topical forms.

Alternatives to Hydrocortisone-Acetic Acid

  • Corticosteroid-only ear drops: Such as hydrocortisone ear drops without acetic acid for non-infectious inflammation.
  • Antibiotic ear drops: For bacterial infections not requiring corticosteroids.
  • Hydrogen peroxide or saline irrigation: For cleaning the ear canal and mild infections.