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Heparin Sodium (Porcine) PF

Heparin is a type of medication known as an anticoagulant or blood thinner. It's used primarily to treat and prevent blood clots in the veins, arteries, or lungs.

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Frequently Asked Questions

Can I safely stop taking heparin?
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No, don't stop taking heparin without your doctor's guidance. Abruptly stopping can increase your risk of blood clots.

Does heparin interact with any foods?
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No, heparin doesn't interact with any foods. However, maintaining a balanced diet is crucial to overall health.

Do I need to monitor my diet while on heparin?
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No, unlike some blood thinners, heparin doesn't require you to follow a special diet.

Will heparin interfere with my other medications?
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Yes, heparin can interact with numerous other medications, including NSAIDs, some heart medications, and other anticoagulants. Always tell your healthcare provider about all the medications you're taking.

Will heparin injection hurt?
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You may feel a slight prick when injecting heparin. Some people also experience minor pain at the injection site after the injection. If this happens, applying a warm compress can help.

Comprehensive Drug Guide

How Does Heparin Sodium (Porcine) PF Work?

Heparin is an anticoagulant medication that inhibits thrombin and Factor Xa – enzymes involved in blood clotting. By doing so, it prevents the formation of blood clots.

What is Heparin Sodium (Porcine) PF Used For?

Heparin is used to treat and prevent blood clots. It's also often used before surgeries to reduce the risk of blood clots.

Common Dosages

  • Injectable solution: 1000, 5000, 10000, 20000, 40000 units per mL


Typical Dosing

FDA Approved Indications

Prophylaxis of Deep Vein Thrombosis (DVT) or Pulmonary Embolism (PE):

  • Subcutaneous (SC) Injection: 5,000 units every 8 to 12 hours.

Treatment of DVT or PE:

  • Intravenous (IV) Bolus: 80 units/kg (or 5,000 units).
  • Continuous IV Infusion: 18 units/kg/hour (or 1,000 units/hour).
  • Adjust based on activated partial thromboplastin time (aPTT) monitoring.


Who Shouldn't Take Heparin Sodium (Porcine) PF?

  • Those with active, uncontrolled bleeding
  • If you have a history of severe allergic reactions to heparin
  • Severe thrombocytopenia (low platelet count)
  • If you have certain medical conditions (e.g., severe uncontrolled high blood pressure, stomach/intestinal ulcers, or bacterial endocarditis)


Advice From The Pharmacist

  • Talk to your Doctor and Pharmacist: You should be in frequent contact with your Healthcare Provider on dosing as it may need to be adjusted occasionally.
  • Expect bruising. A little bruising is normal, but if you notice extensive bruising or blood in your urine or stool, contact your doctor.
  • Regular lab visits. Your healthcare provider may need to monitor your blood regularly for your platelet count and clotting time.
  • Alert for allergic reactions. Notify your healthcare provider if you experience any symptoms of allergic reactions (rashes, hives, difficulty breathing).


Side Effects of Heparin Sodium (Porcine) PF

Common Side Effects

  • You may experience irritation, pain, or redness at the injection site. 


Uncommon/Severe Side Effects

  • Excessive bleeding is rare but can be life-threatening. Symptoms include unusually large or frequent bruises, red or dark brown urine, black or bloody stools, severe nausea/vomiting, and prolonged bleeding from cuts.
  • Heparin can cause decreased platelets in the blood (very rare), which affects blood clotting. Symptoms include easy bruising/bleeding, extreme fatigue, and rapid heartbeat.


Risks and Warnings of Heparin Sodium (Porcine) PF

  • If you have a history of blood disorders, severe liver disease, or stomach or intestinal problems, seek your doctor's approval before beginning the Heparin regime.
  • Its usage might lead to reduced platelet counts leading to severe health implications. Regular blood tests while on this drug can help detect early signs.


Interactions with Heparin Sodium (Porcine) PF

Common Drug Interactions

  • Warfarin
  • Aspirin
  • Nonsteroidal anti-inflammatory drugs (NSAIDs)
  • Platelet inhibitors
  • Thrombin inhibitors


Alternatives to Heparin Sodium (Porcine) PF

  • Warfarin
  • Enoxaparin
  • Dalteparin
  • Fondaparinux
  • Rivaroxaban
  • Apixaban
  • Dabigatran