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Griseofulvin Ultramicrosize
Griseofulvin Ultramicrosize is an antifungal medication used for the treatment of dermatophyte infections of the skin, hair, and nails, including conditions like ringworm (tinea), athlete's foot, and jock itch. The ultramicrosize formulation improves absorption and bioavailability compared to standard griseofulvin, making it effective in treating these infections.
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Frequently Asked Questions
How long does it take for Griseofulvin to work?
Patients may start to see improvement within a few weeks, but complete resolution may take several months, especially for nail infections.
Can I take Griseofulvin if I am pregnant?
Consult your healthcare provider for guidance, as the use of griseofulvin during pregnancy should be carefully considered due to potential risks.
What should I do if I miss a dose?
If you miss a dose, take it as soon as you remember. If it’s close to the next scheduled dose, skip the missed dose and continue with your regular schedule. Do not double up.
Are there any specific storage instructions for Griseofulvin Ultramicrosize?
Store at room temperature, away from moisture and direct sunlight. Keep out of reach of children.
Is Griseofulvin Ultramicrosize safe for long-term use?
While effective, long-term use should be monitored by a healthcare provider to assess efficacy and minimize the risk of side effects.
Comprehensive Drug Guide
How Does Griseofulvin Ultramicrosize Work?
Griseofulvin works by inhibiting fungal cell division. It binds to fungal microtubules, disrupting mitosis (cell division) and preventing the growth and spread of the fungus. This mechanism helps clear the infection from the skin, hair, and nails over time.
Common Dosages
Griseofulvin Ultramicrosize is available in the following forms:
- Oral Tablets: Common strengths include 250 mg.
- Oral Suspension: Typically available in a strength of 125 mg/5 mL.
Typical Dosing
The typical dosing for Griseofulvin Ultramicrosize is:
- For Skin and Nail Infections: The usual adult dose is 500 mg taken orally once daily or divided into two doses, often for several weeks to months, depending on the severity and location of the infection.
Typical Dosing
FDA Approved Indications
Treatment of dermatophyte infections of the skin, hair, and nails, particularly those caused by Trichophyton, Microsporum, and Epidermophyton species.
Who Shouldn't Take Griseofulvin Ultramicrosize?
- Hypersensitivity: Known hypersensitivity to griseofulvin or any components of the formulation.
- Porphyria: Contraindicated in patients with a history of porphyria.
Advice From The Pharmacist
- How to Take: Take with food to enhance absorption and reduce gastrointestinal side effects. Swallow tablets whole; do not crush or chew.
- Regular Monitoring: Follow up with your healthcare provider to monitor the effectiveness of the treatment and any potential side effects.
- Avoid Alcohol: Alcohol consumption should be limited while taking griseofulvin, as it may increase the risk of side effects.
Side Effects of Griseofulvin Ultramicrosize
Common Side Effects
- Nausea
- Diarrhea
- Headache
- Fatigue
Uncommon/Severe Side Effects
- Allergic reactions: Such as rash, itching, or difficulty breathing.
- Liver dysfunction: Monitor for signs of jaundice or elevated liver enzymes.
Risks and Warnings of Griseofulvin Ultramicrosize
- Photosensitivity: Patients should be advised to avoid excessive sunlight and use sunscreen, as griseofulvin may increase sensitivity to sunlight.
- Drug Interactions: Be cautious with other medications that can affect liver metabolism, as they may increase griseofulvin levels.
Interactions with Griseofulvin Ultramicrosize
Common Drug Interactions
- Drug Interactions: Griseofulvin may interact with anticoagulants (e.g., warfarin) and other medications metabolized by the liver. Always consult your healthcare provider for a complete list.
- Food Interactions: Taking griseofulvin with food can enhance its absorption.
Alternatives to Griseofulvin Ultramicrosize
Other Antifungal Medications: Such as terbinafine or itraconazole for systemic treatment of fungal infections.
