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Griseofulvin Microsize
Griseofulvin Microsize is an antifungal medication used primarily for the treatment of dermatophyte infections of the skin, hair, and nails, including conditions like ringworm (tinea), athlete's foot, and jock itch. It works by inhibiting fungal cell division, thus preventing the growth and spread of the fungus.
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Frequently Asked Questions
How long does it take for Griseofulvin to work?
Patients may start to see improvement within a few weeks, but complete resolution of the infection may take several months, especially for nail infections.
Can I take Griseofulvin while pregnant?
Consult your healthcare provider for guidance, as the use of griseofulvin during pregnancy should be carefully considered due to potential risks.
What should I do if I miss a dose?
If you miss a dose, take it as soon as you remember. If it’s close to the next scheduled dose, skip the missed dose and continue with your regular schedule. Do not double up.
Are there any specific storage instructions for Griseofulvin Microsize?
Store at room temperature, away from moisture and direct sunlight. Keep out of reach of children.
Is Griseofulvin safe for long-term use?
While effective, long-term use should be monitored by a healthcare provider to assess efficacy and minimize the risk of side effects.
Comprehensive Drug Guide
How Does Griseofulvin Microsize Work?
Griseofulvin works by binding to fungal microtubules, disrupting mitosis (cell division) and inhibiting the growth of fungal cells. This action leads to the eventual clearance of the infection as the fungus is unable to reproduce.
Common Dosages
Griseofulvin Microsize is available in the following forms:
- Oral Tablets: Common strengths include 125 mg and 250 mg.
- Oral Suspension: Typically available in a strength of 25 mg/mL.
Typical Dosing
The typical dosing for Griseofulvin Microsize is:
- For Skin and Nail Infections: The usual adult dose is 500 mg taken orally once daily or divided into two doses. For children, the dose is typically based on body weight and may be adjusted as necessary.
Typical Dosing
FDA Approved Indications
Treatment of dermatophyte infections of the skin, hair, and nails, particularly those caused by Trichophyton, Microsporum, and Epidermophyton species.
Who Shouldn't Take Griseofulvin Microsize?
- Hypersensitivity: Known hypersensitivity to griseofulvin or any components of the formulation.
- Porphyria: Contraindicated in patients with a history of porphyria.
Advice From The Pharmacist
- How to Take: Take with food to enhance absorption and reduce gastrointestinal side effects. Swallow tablets whole; do not crush or chew.
- Regular Monitoring: Follow up with your healthcare provider to monitor the effectiveness of the treatment and any potential side effects.
- Avoid Alcohol: Alcohol consumption should be limited while taking griseofulvin, as it may increase the risk of side effects.
Side Effects of Griseofulvin Microsize
Common Side Effects
- Nausea
- Diarrhea
- Headache
- Fatigue
Uncommon/Severe Side Effects
- Allergic reactions: Such as rash, itching, or difficulty breathing.
- Liver dysfunction: Monitor for signs of jaundice or elevated liver enzymes.
Risks and Warnings of Griseofulvin Microsize
- Photosensitivity: Patients should be advised to avoid excessive sunlight and use sunscreen, as griseofulvin may increase sensitivity to sunlight.
- Drug Interactions: Inform your healthcare provider about all medications you are taking, as griseofulvin may interact with anticoagulants and other drugs metabolized by the liver.
Interactions with Griseofulvin Microsize
Common Drug Interactions
- Drug Interactions: Griseofulvin may interact with anticoagulants (e.g., warfarin) and other medications that induce or inhibit liver enzymes. Always consult your healthcare provider for a complete list.
- Food Interactions: Taking griseofulvin with food can enhance its absorption.
Alternatives to Griseofulvin Microsize
Other Antifungal Medications: Such as terbinafine or itraconazole for systemic treatment of fungal infections.
