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Gardasil 9

Gardasil 9 is a human papillomavirus (HPV) vaccine designed to protect against nine types of HPV, which are responsible for the majority of HPV-related cancers and diseases. This vaccine is indicated for the prevention of cervical, vulvar, vaginal, anal, and oropharyngeal cancers, as well as genital warts. Gardasil 9 is recommended for preteens, adolescents, and young adults, and it plays a critical role in reducing the incidence of HPV-related health issues.



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Frequently Asked Questions

How effective is Gardasil 9?
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Gardasil 9 is highly effective in preventing infections and diseases caused by the HPV types it covers, significantly reducing the risk of related cancers and genital warts.

Can Gardasil 9 be given to adults?
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Yes, Gardasil 9 is approved for use in individuals up to age 45. Consult a healthcare provider for recommendations.

What should I do if I miss a dose?
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If a dose is missed, schedule it as soon as possible. Follow up to complete the series according to the recommended intervals.

Are there any specific storage instructions for Gardasil 9?
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Gardasil 9 should be stored in a refrigerator (2°C to 8°C or 36°F to 46°F). Do not freeze.

Can I receive Gardasil 9 if I am pregnant?
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While there are no known risks, it is generally recommended to receive the vaccine before pregnancy. Consult your healthcare provider for specific guidance.

Comprehensive Drug Guide

How Does Gardasil 9 Work?

Gardasil 9 works by stimulating the immune system to produce antibodies against specific HPV types. It contains non-infectious virus-like particles (VLPs) that mimic the structure of HPV, allowing the immune system to recognize and attack the virus if exposed in the future. By generating an immune response, the vaccine helps prevent the development of HPV-related cancers and diseases.



Common Dosages

  • Injection: Each dose contains 0.5 mL of vaccine.

Typical Dosing

The typical dosing schedule for Gardasil 9 is:

  • For individuals aged 9 to 14: Two doses are administered; the second dose is given 6-12 months after the first dose.
  • For individuals aged 15 and older: Three doses are administered; the second dose is given 1-2 months after the first dose, and the third dose is given 6 months after the first dose.

Typical Dosing

FDA Approved Indications

  • Prevention of certain cancers caused by HPV types 16, 18, 31, 33, 45, 52, and 58.
  • Prevention of genital warts caused by HPV types 6 and 11.

Who Shouldn't Take Gardasil 9?

  • Severe Allergic Reaction: Known hypersensitivity to any component of the vaccine.
  • Pregnancy: While there are no known risks, vaccination is generally recommended before pregnancy.

Advice From The Pharmacist

  • How to Administer: Gardasil 9 is administered as an intramuscular injection, typically in the deltoid muscle of the upper arm or the thigh.
  • Monitoring: Observe patients for 15 minutes after vaccination to monitor for any immediate allergic reactions.
  • Follow-Up: Ensure patients return for the full vaccination series according to the recommended schedule for maximum efficacy.

Side Effects of Gardasil 9

Common Side Effects

  • Injection site reactions: Pain, redness, swelling.
  • Fever
  • Headache
  • Nausea


Uncommon/Severe Side Effects

Severe allergic reactions: Such as anaphylaxis.

Risks and Warnings of Gardasil 9

  • Syncope: There is a risk of fainting (syncope) following vaccination; ensure proper supervision after administration.
  • Not for Treatment: Gardasil 9 is not a treatment for existing HPV infections or diseases.
  • Pregnancy: While there is no evidence of risk, vaccination is not recommended during pregnancy.

Interactions with Gardasil 9

Common Drug Interactions

  • Drug Interactions: There are no known significant drug interactions with Gardasil 9; however, inform the healthcare provider of all medications being taken.
  • Other Vaccines: Gardasil 9 can be administered simultaneously with other vaccines, but they should be given at separate injection sites.

Alternatives to Gardasil 9

Cervarix: Another HPV vaccine that targets HPV types 16 and 18 but does not cover types 6, 11, 31, 33, 45, 52, and 58.