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Fyavolv

Fyavolv (generic name: norethindrone acetate and ethinyl estradiol) is a combination hormone therapy used to treat menopausal symptoms, such as hot flashes, vaginal dryness, and bone loss prevention in postmenopausal women. It contains norethindrone acetate, a progestin, and ethinyl estradiol, a synthetic estrogen.



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Frequently Asked Questions

Can Fyavolv be used for long-term therapy?
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Long-term hormone replacement therapy should be used at the lowest effective dose and for the shortest duration necessary. Consult your healthcare provider about how long you should take Fyavolv.

Does Fyavolv cause weight gain?
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Fyavolv may cause weight changes, but this varies by individual. Consult your healthcare provider if you have concerns.

Can I take Fyavolv if I smoke?
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Women who smoke and are over the age of 35 are at higher risk of serious side effects like blood clots. Quitting smoking is highly recommended.

Does Fyavolv help with osteoporosis?
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Fyavolv is approved for osteoporosis prevention in postmenopausal women, but it should not be used solely for this purpose. Ensure you have adequate calcium and vitamin D intake.

Can I stop Fyavolv abruptly?
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Do not stop taking Fyavolv without consulting your healthcare provider. Stopping abruptly can cause a return of menopausal symptoms.

Comprehensive Drug Guide

How Does Fyavolv Work?

Fyavolv provides estrogen and progestin to help regulate hormonal balance in postmenopausal women. Estrogen helps alleviate menopausal symptoms, while progestin prevents the overgrowth of the uterine lining caused by estrogen.



Common Dosages

  • 0.5 mg norethindrone acetate / 2.5 mcg ethinyl estradiol tablets

Typical Dosing

  • Take one tablet daily, at the same time each day.


Typical Dosing

FDA Approved Indications

  • Treatment of moderate to severe vasomotor symptoms associated with menopause (e.g., hot flashes)
  • Prevention of osteoporosis in postmenopausal women


Who Shouldn't Take Fyavolv?

  • Breast cancer
  • Liver disease
  • Undiagnosed vaginal bleeding
  • History of blood clots


Advice From The Pharmacist

  • Take Fyavolv at the same time every day, with or without food.
  • Inform your healthcare provider if you experience vaginal bleeding, breast lumps, or vision changes while on Fyavolv.
  • Ensure regular breast exams and mammograms while using hormone replacement therapy.


Side Effects of Fyavolv

Common Side Effects

  • Nausea
  • Breast tenderness
  • Headache
  • Weight gain


Uncommon/Severe Side Effects

  • Blood clots
  • Stroke
  • Breast cancer


Risks and Warnings of Fyavolv

  • Blood Clots: Fyavolv can increase the risk of blood clots, especially in women who smoke or are over the age of 35.
  • Breast Cancer: Long-term use of estrogen and progestin can increase the risk of breast cancer. Regular checkups and screenings are recommended.


Interactions with Fyavolv

Common Drug Interactions

  • Anticonvulsants: Some medications for seizures can decrease the effectiveness of Fyavolv.
  • St. John’s Wort: This herbal supplement can reduce the effectiveness of Fyavolv.


Alternatives to Fyavolv

  • Premarin: A commonly prescribed estrogen therapy for menopausal symptoms.
  • Estrace: Another estrogen replacement therapy used for menopausal symptoms.
  • Activella: A combination of estradiol and norethindrone acetate for hormone replacement therapy.