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Fosinopril Sodium
Fosinopril Sodium is an ACE inhibitor used to treat high blood pressure (hypertension) and heart failure. It works by inhibiting the angiotensin-converting enzyme (ACE), which helps to relax blood vessels and reduce blood pressure. Fosinopril also helps improve heart function and reduce symptoms of heart failure by lowering the strain on the heart.
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Frequently Asked Questions
How long does it take for Fosinopril to start working?
Fosinopril may take a few weeks to show its full effect in lowering blood pressure. However, improvements in symptoms of heart failure may be noticed sooner.
Can I stop taking Fosinopril if I feel better?
You should not stop taking Fosinopril without consulting your healthcare provider, as this could lead to a rebound in blood pressure or worsening of heart failure symptoms.
Are there any lifestyle changes I should make while taking Fosinopril?
It's beneficial to follow a healthy diet low in salt and maintain a regular exercise routine. Regular check-ups and monitoring of blood pressure and kidney function are also important.
What should I do if I miss a dose?
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose—do not double up to make up for a missed dose.
Comprehensive Drug Guide
How Does Fosinopril Sodium Work?
Fosinopril Sodium works by inhibiting the angiotensin-converting enzyme (ACE), which is involved in the conversion of angiotensin I to angiotensin II. Angiotensin II is a substance that constricts blood vessels and raises blood pressure. By blocking this conversion, Fosinopril causes blood vessels to relax and widen, resulting in lower blood pressure and reduced workload on the heart.
Common Dosages
- Oral tablets: 10 mg, 20 mg, 40 mg
Typical Dosing
The typical dosing for Fosinopril Sodium is:
- For Hypertension: The initial dose is usually 10 mg once daily, which can be adjusted based on response, up to a maximum of 40 mg per day.
- For Heart Failure: The initial dose is usually 10 mg once daily, with adjustments based on patient response, up to a maximum of 40 mg per day.
Typical Dosing
FDA Approved Indications
- Hypertension (high blood pressure)
- Heart Failure
Who Shouldn't Take Fosinopril Sodium?
- Hypersensitivity: Patients with a known hypersensitivity to Fosinopril or any ACE inhibitors.
- Pregnancy: Use in pregnant women is contraindicated due to potential harm to the fetus.
- History of Angioedema: Patients who have experienced angioedema related to previous ACE inhibitor therapy should avoid Fosinopril.
Advice From The Pharmacist
- Administration: Take the medication exactly as prescribed, with or without food. Try to take it at the same time each day to maintain a consistent level in your body.
- Monitoring: Regular blood pressure monitoring is necessary to ensure the drug is effective and to adjust the dose if needed.
- Avoiding Potassium: Be cautious with potassium supplements or salt substitutes containing potassium, as Fosinopril can increase potassium levels in the blood.
- Consult Healthcare Providers: Notify your healthcare provider of any new symptoms or if you experience persistent cough, dizziness, or swelling of the face or limbs.
Side Effects of Fosinopril Sodium
Common Side Effects
- Dizziness
- Headache
- Cough
- Fatigue
Uncommon/Severe Side Effects
- Angioedema (swelling of the face, lips, tongue, or throat)
- Severe hypotension (very low blood pressure)
- Kidney dysfunction (elevated blood urea nitrogen or serum creatinine)
Risks and Warnings of Fosinopril Sodium
- Pregnancy: Fosinopril can cause harm to the fetus, including renal impairment, skull malformations, and even death. It should not be used during pregnancy.
- Renal Impairment: Use with caution in patients with renal impairment, as it can further impact kidney function.
- Hypotension: Initial treatment may cause a significant drop in blood pressure, especially in patients who are volume-depleted or on diuretics.
Interactions with Fosinopril Sodium
Common Drug Interactions
- Drug Interactions: Fosinopril may interact with other antihypertensives, potassium-sparing diuretics, and non-steroidal anti-inflammatory drugs (NSAIDs). These interactions can increase the risk of hyperkalemia or reduce the effectiveness of Fosinopril.
- Food Interactions: There are no significant food interactions, but maintaining a consistent diet is recommended.
- Allergies: Patients with a history of angioedema related to ACE inhibitors should avoid using Fosinopril.
Common Food Interactions
Alternatives to Fosinopril Sodium
- Other ACE Inhibitors: Lisinopril, enalapril, ramipril
- Angiotensin II Receptor Blockers (ARBs): Losartan, valsartan, candesartan
- Calcium Channel Blockers: Amlodipine, diltiazem
- Beta-Blockers: Metoprolol, atenolol
