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Flulaval Quadrivalent
Flulaval Quadrivalent is an inactivated influenza vaccine that provides protection against four strains of the influenza virus (two A strains and two B strains). It is designed to help prevent seasonal influenza (flu) and reduce the risk of complications such as pneumonia, bronchitis, and other respiratory illnesses. Flulaval Quadrivalent is suitable for individuals 6 months and older and helps the immune system develop antibodies that protect against the flu virus.
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Frequently Asked Questions
How is Flulaval Quadrivalent different from other flu vaccines?
Flulaval Quadrivalent provides protection against four strains of the flu virus (two A strains and two B strains), offering broader protection compared to trivalent vaccines, which cover only three strains.
Can Flulaval Quadrivalent cause the flu?
No, Flulaval contains inactivated viruses, so it cannot cause the flu. Mild side effects like soreness or a low-grade fever are normal immune responses.
How long does it take for the vaccine to work?
It takes about two weeks for the body to develop immunity after receiving the vaccine, so it is best to get vaccinated before flu season begins.
Who should receive Flulaval Quadrivalent?
Flulaval is recommended for everyone aged 6 months and older, particularly those at high risk for flu-related complications, such as the elderly, pregnant women, young children, and people with chronic health conditions.
Can I get the flu vaccine if I have an egg allergy?
Most people with mild egg allergies can receive Flulaval Quadrivalent under medical supervision. However, individuals with severe egg allergies may consider Flucelvax or Flublok, which are egg-free alternatives.
Comprehensive Drug Guide
How Does Flulaval Quadrivalent Work?
Flulaval Quadrivalent contains inactivated (killed) influenza viruses that stimulate the immune system to produce antibodies against the virus. These antibodies provide protection against future infections by the same or similar strains of the virus. The vaccine covers two A strains and two B strains of the flu virus, offering broader protection compared to trivalent vaccines, which cover only three strains.
Common Dosages
The standard dosage for Flulaval Quadrivalent is:
- 0.5 mL administered as a single intramuscular injection per flu season.
Typical Dosing
- For adults and children aged 6 months and older: One 0.5 mL intramuscular injection per flu season, typically administered in the deltoid muscle (upper arm) for adults and in the thigh or upper arm for young children.
- For children aged 6 months to 8 years who are receiving the flu vaccine for the first time, two doses may be required, given at least four weeks apart.
Typical Dosing
FDA Approved Indications
Active immunization against influenza in individuals aged 6 months and older to help prevent the flu and its related complications.
Who Shouldn't Take Flulaval Quadrivalent?
- Severe allergic reactions (e.g., anaphylaxis) to any component of the vaccine, including egg proteins.
- A history of severe allergic reactions following a previous dose of any influenza vaccine.
Advice From The Pharmacist
- Get vaccinated annually, as the flu virus strains change each year, and the vaccine is updated to match the most likely circulating strains.
- Flulaval cannot cause the flu because it contains inactivated viruses. However, mild side effects like soreness at the injection site or mild fever are common.
- If you have a history of egg allergies, discuss with your healthcare provider before receiving Flulaval Quadrivalent. In most cases, it is still safe to administer under medical supervision.
- The vaccine is administered as an intramuscular injection in the upper arm or thigh for young children.
Side Effects of Flulaval Quadrivalent
Common Side Effects
- Soreness, redness, or swelling at the injection site
- Muscle aches
- Headache
- Fatigue
- Low-grade fever
Uncommon/Severe Side Effects
- Severe allergic reactions (e.g., difficulty breathing, swelling of the face or throat)
- Guillain-Barré Syndrome (GBS), though this is extremely rare.
Risks and Warnings of Flulaval Quadrivalent
- Allergic Reactions: Individuals with severe allergies to the vaccine or its components, especially egg proteins, should avoid receiving the vaccine or receive it under medical supervision.
- Guillain-Barré Syndrome (GBS): There is a small risk of GBS following influenza vaccination, although the risk is extremely low. Individuals with a history of GBS should consult with their healthcare provider before receiving the vaccine.
- Effectiveness: While Flulaval Quadrivalent significantly reduces the risk of contracting the flu, no vaccine provides 100% protection. It's still important to practice good hygiene and take precautions to avoid the flu.
Interactions with Flulaval Quadrivalent
Common Drug Interactions
- Other vaccines: Flulaval Quadrivalent can be administered with other vaccines, but each should be given at different injection sites.
- Immunosuppressive medications: Individuals taking medications that suppress the immune system may have a reduced response to the vaccine and should discuss this with their healthcare provider.
Alternatives to Flulaval Quadrivalent
- Fluzone High-Dose Quadrivalent: A higher-dose flu vaccine designed for individuals aged 65 and older to provide enhanced protection.
- Flucelvax Quadrivalent: A cell culture-based flu vaccine that is free from egg proteins, suitable for individuals with egg allergies.
- Flublok Quadrivalent: A recombinant flu vaccine that is free from egg proteins, suitable for individuals aged 18 and older.
- Fluad Quadrivalent: An adjuvanted flu vaccine designed to enhance the immune response in individuals aged 65 and older.
