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Fluarix Quadrivalent

Fluarix Quadrivalent is an inactivated influenza vaccine that provides protection against four strains of the influenza virus (two A strains and two B strains). It is designed to prevent seasonal influenza (flu) and reduce the risk of flu-related complications such as pneumonia, bronchitis, and other serious conditions. The vaccine is recommended for individuals 6 months and older and helps the immune system develop antibodies that protect against the flu.



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Frequently Asked Questions

How is Fluarix Quadrivalent different from other flu vaccines?
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Fluarix Quadrivalent contains four strains of the flu virus (two A strains and two B strains) to provide broader protection compared to trivalent vaccines, which cover only three strains.

Can Fluarix Quadrivalent cause the flu?
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No, Fluarix contains inactivated viruses, meaning it cannot cause the flu. Some people may experience mild side effects like soreness or fever, but these are normal immune responses.

How long does it take for the vaccine to work?
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It takes about two weeks for the body to develop immunity after receiving the vaccine. It is best to get vaccinated before the flu season begins.

Who should receive Fluarix Quadrivalent?
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Fluarix is recommended for everyone aged 6 months and older, especially high-risk groups like the elderly, pregnant women, young children, and those with chronic health conditions.

Can I get the flu vaccine if I have an egg allergy?
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If you have a history of mild egg allergies, Fluarix may still be administered under medical supervision. For individuals with severe egg allergies, alternatives like Flublok or Flucelvax (which are egg-free) may be considered.

Comprehensive Drug Guide

How Does Fluarix Quadrivalent Work?

Fluarix Quadrivalent contains inactivated (killed) influenza viruses that cannot cause the flu but stimulate the immune system to produce antibodies. These antibodies provide protection against future infections by the same strains of the virus. By including two A strains and two B strains, the vaccine covers the most likely circulating strains of influenza for the given flu season.



Common Dosages

The typical dosage of Fluarix Quadrivalent is:

  • 0.5 mL administered as a single intramuscular injection per flu season.
  • For adults and children 6 months and older: One 0.5 mL intramuscular injection per flu season. The preferred injection site is the deltoid muscle (upper arm) for adults and children, while young children may receive the injection in the thigh.
  • For children aged 6 months to 8 years receiving the flu vaccine for the first time, two doses may be required, given at least four weeks apart.

Typical Dosing

FDA Approved Indications

  • Active immunization against influenza in individuals aged 6 months and older to prevent the flu and related complications.


Who Shouldn't Take Fluarix Quadrivalent?

  • Severe allergic reactions (e.g., anaphylaxis) to any component of the vaccine, including egg proteins.
  • A history of severe allergic reactions following a previous dose of any flu vaccine.

Advice From The Pharmacist

  • Get vaccinated annually, as the flu virus strains change each year, and new vaccines are developed to match the current circulating strains.
  • Fluarix cannot cause the flu because it contains inactivated viruses, but mild side effects like soreness at the injection site or mild fever may occur.
  • If you have a history of severe egg allergies, discuss with your healthcare provider before receiving Fluarix Quadrivalent. In many cases, it is still safe to administer under medical supervision.
  • The vaccine is typically given in the upper arm (deltoid) for adults and in the thigh or upper arm for young children.

Side Effects of Fluarix Quadrivalent

Common Side Effects

  • Pain, redness, or swelling at the injection site
  • Muscle aches
  • Headache
  • Fatigue
  • Low-grade fever


Uncommon/Severe Side Effects

  • Severe allergic reactions (anaphylaxis), including difficulty breathing, swelling of the face or throat, and hives.
  • Guillain-Barré syndrome (GBS), though the risk is extremely low.

Risks and Warnings of Fluarix Quadrivalent

  • Allergic Reactions: People who have had a severe allergic reaction to any flu vaccine or its components should avoid getting Fluarix Quadrivalent.
  • Guillain-Barré Syndrome (GBS): Although the risk is very low, individuals with a history of GBS should discuss vaccination with their healthcare provider.
  • Effectiveness: While Fluarix significantly reduces the risk of contracting the flu, no vaccine provides 100% protection. Continuing preventive measures, such as handwashing and avoiding contact with sick individuals, is advised.

Interactions with Fluarix Quadrivalent

Common Drug Interactions

  • Other vaccines: Fluarix can be administered with other vaccines but at different injection sites.
  • Immunosuppressive therapies: Individuals taking immunosuppressive drugs (e.g., corticosteroids, chemotherapy) may have a reduced immune response to the vaccine.

Alternatives to Fluarix Quadrivalent

  • Fluzone High-Dose Quadrivalent: A higher-dose flu vaccine designed for individuals aged 65 and older to provide enhanced protection.
  • Fluad Quadrivalent: An adjuvanted flu vaccine recommended for adults aged 65 and older, designed to boost the immune response in older adults.
  • Flucelvax Quadrivalent: A cell culture-based flu vaccine that is free from egg proteins, suitable for individuals with egg allergies.
  • Flublok Quadrivalent: A recombinant flu vaccine made without eggs, suitable for individuals aged 18 and older.