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Filspari
Filspari is an immunomodulatory drug used to treat multiple sclerosis. It reduces the frequency of relapse and delays the progression of disability. Some common side effects include flushing, stomach pain, and hot flush, but your doctor will usually ensure the benefits of taking this medication outweigh these issues.
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Frequently Asked Questions
Can Filspari cause side effects?
Yes, like all medications, Filspari can cause side effects.
How should I take Filspari?
Take Filspari once a day. Try to take it at the same time each day.
What should I avoid while taking Filspari?
While taking Filspari, avoid live vaccines and contact with people who have recently received live vaccines due to an increased risk of infection.
What should I do if I miss a dose of Filspari?
If you have missed a dose of Filspari, take it as soon as you remember. However, if it?s almost time for your next dose, skip the missed dose, and then resume your usual schedule.
Comprehensive Drug Guide
How Does Filspari Work?
Filspari is an immunomodulatory drug that impacts the function of specific types of white blood cells in the immune system. It reduces neuroinflammation by restricting the ability of white blood cells to cross the bloodbrain barrier and damage the nerve cells.
What is Filspari Used For?
FDA indications: Filspari is used for the treatment of relapsing forms of multiple sclerosis (MS), including clinically isolated syndrome, relapsingremitting disease, and active secondary progressive disease.
Common Dosages
Capsules: 0.25 mg, 0.5mg
Typical Dosing
FDA Approved Indications
- Multiple Sclerosis: 0.25mg or 0.50mg once daily, taken by mouth.
Who Shouldn't Take Filspari?
- Have a history of hypersensitivity to fingolimod or any of the excipients.
- Have had a recent (last 6 months) heart attack, unstable angina, stroke, or certain types of heart failure.
- On Class Ia or Class III antiarrhythmic drugs.
- Have baseline QTc intervals ? 500 ms.
Advice From The Pharmacist
- Take Filspari exactly as instructed by your doctor.
- Do not break or crush the medication. It should be swallowed whole with a glass of water.
- Inform your doctor of any changes in your health during your course of treatment.
- Monitor your heart condition and consult your doctor should you experience irregular heartbeats or palpitations.
- Don't abruptly stop taking Filspari without your doctor's advice as it may worsen your condition.
Side Effects of Filspari
Common Side Effects
- Flushing (warmth, redness, itching, or tingling of the skin)
- Stomach pain
- Diarrhea
- Back pain
Uncommon/Severe Side Effects
- Uncommon side effects:
- Fatigue
- Dizziness
- Cough
- Rare side effects:
- Allergic reactions
- Severe skin reactions
- Muscle pain or weakness
- Vision problems
- Severe side effects:
- Slow heart rate
- Increased risk of infections
- Shortness of breath
Risks and Warnings of Filspari
- Heart conditions should be managed before beginning Filspari.
- Potential for serious infections due to the drug's effect on the immune system.
- Your doctor should monitor your heart rate for at least 6 hours after your first dose.
- Regular ophthalmology exams are recommended to monitor your vision.
- Warns against use in pregnant women due to potential fetal harm.
Interactions with Filspari
Common Drug Interactions
- Betablockers
- Heart ratelowering calcium channel blockers
- Other drugs that slow the heart rate or electrical impulse conduction in the heart
- Vaccines
Alternatives to Filspari
- Avonex
- Betaseron
- Copaxone
- Extavia
- Nabiga
- Ocrevus
- Rebif
- Tecfidera
- Tysabri
