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Evoxac

Evoxac (cevimeline) is a muscarinic agonist used to treat dry mouth (xerostomia) in patients with Sjögren's syndrome, an autoimmune disorder that affects the moisture-producing glands. It helps stimulate saliva production to relieve the symptoms of dry mouth.



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Frequently Asked Questions

How quickly does Evoxac work?
Open FAQClose FAQ

Most patients notice improvement in dry mouth symptoms within 1 to 2 weeks of starting Evoxac.

Can Evoxac cause excessive sweating?
Open FAQClose FAQ

Yes, Evoxac can increase sweating as it stimulates muscarinic receptors in the body.

Is Evoxac safe for long-term use?
Open FAQClose FAQ

Evoxac is generally safe for long-term use, but regular monitoring by your healthcare provider is recommended.

Can I drink alcohol while taking Evoxac?
Open FAQClose FAQ

Alcohol may worsen dry mouth symptoms and can interfere with the effectiveness of Evoxac, so it’s best to limit alcohol consumption.

What should I do if I miss a dose of Evoxac?
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If you miss a dose, take it as soon as you remember. If it's almost time for your next dose, skip the missed dose and continue with your regular schedule.

Comprehensive Drug Guide

How Does Evoxac Work?

Evoxac works by stimulating muscarinic receptors in the salivary glands, increasing the production of saliva and improving symptoms of dry mouth in patients with Sjögren's syndrome.



Common Dosages

  • Capsules: 30 mg

Typical Dosing

  • The typical dose for Evoxac is 30 mg taken three times daily.



Typical Dosing

FDA Approved Indications

  • Treatment of dry mouth (xerostomia) in patients with Sjögren's syndrome.


Who Shouldn't Take Evoxac?

  • Known hypersensitivity to cevimeline or any of the ingredients.
  • Uncontrolled asthma or narrow-angle glaucoma.


Advice From The Pharmacist

  • Take Evoxac with food or without food, but try to take it at the same time each day for consistent results.
  • If you miss a dose, take it as soon as you remember unless it's close to your next dose.
  • Stay hydrated while taking Evoxac to help improve dry mouth symptoms.


Side Effects of Evoxac

Common Side Effects

  • Sweating
  • Nausea
  • Runny nose
  • Increased urinary frequency


Uncommon/Severe Side Effects

  • Worsening of asthma or respiratory conditions
  • Heart rhythm problems


Risks and Warnings of Evoxac

  • Respiratory Risk: Evoxac may worsen asthma or other respiratory conditions, so it is not recommended for patients with uncontrolled asthma.
  • Heart Disease: Evoxac may affect heart rhythm in patients with preexisting heart conditions.


Interactions with Evoxac

Common Drug Interactions

  • Beta-blockers: May increase the risk of heart rhythm abnormalities when taken with Evoxac.
  • Anticholinergic medications: May counteract the effects of Evoxac, reducing its effectiveness.


Alternatives to Evoxac

  • Salagen (pilocarpine)
  • Biotene (artificial saliva substitute)
  • Mouth sprays and lozenges for dry mouth