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Evamist
Evamist (generic name: estradiol transdermal spray) is a topical hormone replacement therapy (HRT) used to treat menopausal symptoms, such as hot flashes. It contains estradiol, a form of estrogen, which helps to alleviate symptoms caused by low estrogen levels during menopause.
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Frequently Asked Questions
How long does it take for Evamist to work?
Evamist may take several weeks to relieve menopausal symptoms like hot flashes, though some patients notice improvements within a few days.
Can I apply Evamist to any part of my body?
No, Evamist should be applied to the inside of the forearm, where it is absorbed most effectively.
Can I shower after applying Evamist?
Wait at least 1 hour after applying Evamist before showering or swimming.
Does Evamist increase the risk of breast cancer?
Long-term estrogen therapy may increase the risk of breast cancer. Discuss with your doctor whether hormone therapy is right for you.
Can I use Evamist if I’m still having menstrual periods?
Evamist is typically prescribed for postmenopausal women, so consult your doctor if you are still menstruating.
Comprehensive Drug Guide
How Does Evamist Work?
Evamist works by delivering estradiol through the skin into the bloodstream. This estrogen helps to alleviate the symptoms of menopause, including hot flashes and night sweats, by restoring hormonal balance.
Common Dosages
- Evamist is available as a transdermal spray, with each spray delivering 90 mcg of estradiol.
Typical Dosing
- The typical starting dose is one spray applied daily to the skin on the inside of the forearm, though the dose may be adjusted by your healthcare provider.
Typical Dosing
FDA Approved Indications
- Moderate to severe vasomotor symptoms associated with menopause
Who Shouldn't Take Evamist?
- Undiagnosed abnormal vaginal bleeding
- Breast cancer
- History of thromboembolic events (blood clots)
- Liver disease
Advice From The Pharmacist
- Apply Evamist to the inside of the forearm, and allow it to dry completely before covering with clothing.
- Avoid contact with the eyes or mouth.
- Evamist should not be applied to the breasts.
- If you miss a dose, apply it as soon as you remember. Do not double the dose.
Side Effects of Evamist
Common Side Effects
- Breast tenderness
- Headache
- Skin irritation
Uncommon/Severe Side Effects
- Blood clots
- Breast or uterine cancer
- Stroke
Risks and Warnings of Evamist
- Blood Clots: Estrogen use increases the risk of blood clots, particularly in women over 50. Use the lowest effective dose for the shortest duration.
- Cancer Risk: Long-term estrogen therapy may increase the risk of breast cancer and endometrial cancer. Women with a uterus may require progestin in addition to estrogen therapy to reduce this risk.
Interactions with Evamist
Common Drug Interactions
- Warfarin: Estrogen may affect the efficacy of warfarin, requiring dosage adjustments.
- CYP3A4 inhibitors: These medications may alter the metabolism of estradiol, affecting its levels in the body.
Alternatives to Evamist
- Climara: A transdermal estrogen patch used for hormone replacement therapy.
- Estrace: Oral or vaginal estrogen replacement therapy for menopausal symptoms.
- Premarin: A conjugated estrogen tablet or cream used for menopause-related symptoms.
