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Equetro
Equetro is an anticonvulsant and mood stabilizer used to treat bipolar disorder and certain types of seizures, including epilepsy and trigeminal neuralgia. It helps to reduce the frequency of mood swings in bipolar disorder and controls abnormal electrical activity in the brain to prevent seizures. Equetro is a form of extended-release carbamazepine.
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Frequently Asked Questions
Can I drink alcohol while taking Equetro?
No, alcohol can increase the sedative effects of Equetro and heighten the risk of seizures or mood instability.
How long does it take for Equetro to work for bipolar disorder?
It may take several weeks for Equetro to stabilize mood in patients with bipolar disorder.
Can Equetro cause weight gain?
Some patients may experience weight gain while taking Equetro, though this is not a common side effect.
Does Equetro interact with birth control pills?
Yes, Equetro can reduce the effectiveness of oral contraceptives, so using alternative or backup contraception is recommended.
What should I do if I miss a dose of Equetro?
Take the missed dose as soon as you remember. If it’s close to the time of your next dose, skip the missed dose and resume your regular schedule. Do not double up doses.
Comprehensive Drug Guide
How Does Equetro Work?
Equetro works by blocking sodium channels in the brain, which reduces abnormal electrical activity. This action helps control seizures and stabilizes mood in patients with bipolar disorder.
Common Dosages
- Extended-release capsules: 100 mg, 200 mg, and 300 mg
Typical Dosing
- For bipolar disorder, the typical starting dose is 200 mg twice daily, which can be increased gradually.
- For seizures, the starting dose is 200 mg once or twice daily, with adjustments based on response.
Typical Dosing
FDA Approved Indications
- Bipolar disorder (acute manic or mixed episodes)
- Epilepsy (partial seizures and generalized tonic-clonic seizures)
- Trigeminal neuralgia (nerve pain in the face)
Who Shouldn't Take Equetro?
- Known hypersensitivity to carbamazepine or tricyclic antidepressants.
- History of bone marrow depression.
- Concomitant use of MAO inhibitors.
Advice From The Pharmacist
- Take Equetro with food to reduce stomach upset.
- Regular blood tests may be needed to monitor for potential side effects such as blood cell counts or liver function.
- Do not stop taking Equetro suddenly, as it can trigger seizures or withdrawal symptoms.
Side Effects of Equetro
Common Side Effects
- Dizziness
- Drowsiness
- Nausea
- Blurred vision
Uncommon/Severe Side Effects
- Severe skin reactions (Stevens-Johnson syndrome)
- Bone marrow suppression
- Liver damage
Risks and Warnings of Equetro
- Serious Skin Reactions: Equetro can cause severe skin reactions, especially in patients of Asian descent. Testing for the HLA-B*1502 gene is recommended before starting treatment.
- Blood Cell Abnormalities: Equetro may cause aplastic anemia or agranulocytosis, so regular monitoring of blood counts is necessary.
Interactions with Equetro
Common Drug Interactions
- Grapefruit juice: Can increase the levels of carbamazepine in the blood, leading to potential toxicity.
- Oral contraceptives: Equetro can reduce the effectiveness of birth control pills, so alternative contraception methods are advised.
Alternatives to Equetro
- Lamictal (lamotrigine)
- Depakote (valproate)
- Lithium (used for bipolar disorder)
