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Epitol
Epitol (carbamazepine) is an anticonvulsant and mood stabilizer used to treat seizure disorders such as epilepsy, trigeminal neuralgia (a condition that causes severe facial pain), and bipolar disorder. It works by reducing abnormal electrical activity in the brain. Epitol belongs to the dibenzazepine anticonvulsant drug class.
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Frequently Asked Questions
How long does it take for Epitol to start working?
It may take several days to weeks for Epitol to reach its full effect, especially for mood stabilization or nerve pain relief.
Can I drink alcohol while taking Epitol?
No, alcohol can increase the sedative effects of Epitol and increase the risk of seizures or side effects.
Can Epitol be used for bipolar disorder?
Yes, Epitol is often used as a mood stabilizer for patients with bipolar disorder to prevent mood swings.
Does Epitol interact with birth control pills?
Yes, Epitol can decrease the effectiveness of birth control pills. Consider using alternative methods of contraception while on this medication.
What should I do if I miss a dose of Epitol?
Take the missed dose as soon as you remember. If it is close to your next dose, skip the missed dose and continue with your regular schedule. Do not double up doses.
Comprehensive Drug Guide
How Does Epitol Work?
Epitol works by blocking sodium channels in the brain, which helps prevent abnormal electrical discharges that cause seizures and nerve pain. It also stabilizes mood in patients with bipolar disorder by modulating neurotransmitter activity.
Common Dosages
- Tablet form: 200 mg
- Extended-release tablets: 100 mg, 200 mg, 400 mg
Typical Dosing
- For epilepsy, the usual starting dose is 200 mg twice daily, which may be increased gradually based on response.
- For trigeminal neuralgia, the starting dose is 100 mg twice daily, increasing as needed.
Typical Dosing
FDA Approved Indications
- Epilepsy (partial and generalized seizures)
- Trigeminal neuralgia
- Bipolar disorder (as a mood stabilizer)
Who Shouldn't Take Epitol?
- Known hypersensitivity to carbamazepine or any of its components.
- History of bone marrow depression.
- Concomitant use of MAO inhibitors.
Advice From The Pharmacist
- Take Epitol with food to reduce stomach upset.
- Regular blood tests may be needed to monitor for potential side effects, especially blood cell counts and liver function.
- Do not stop taking Epitol suddenly, as this may trigger seizures or other withdrawal symptoms.
Side Effects of Epitol
Common Side Effects
- Dizziness
- Drowsiness
- Nausea
- Blurred vision
Uncommon/Severe Side Effects
- Severe skin reactions (Stevens-Johnson syndrome)
- Bone marrow suppression
- Liver damage
Risks and Warnings of Epitol
- Severe Skin Reactions: Patients of Asian descent should be tested for HLA-B*1502 gene before starting Epitol, as they are at higher risk for severe skin reactions.
- Blood Cell Abnormalities: Epitol may cause aplastic anemia or agranulocytosis. Regular monitoring of blood counts is important.
Interactions with Epitol
Common Drug Interactions
- MAO inhibitors: Should not be used with Epitol.
- Grapefruit juice: Can increase the levels of carbamazepine in the blood, leading to toxicity.
- Oral contraceptives: Epitol can reduce the effectiveness of birth control pills, so alternative contraception methods may be necessary.
Alternatives to Epitol
- Lamictal (lamotrigine)
- Depakote (valproate)
- Topamax (topiramate)
