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Epaned
Epaned (enalapril maleate) is an ACE inhibitor used to treat high blood pressure (hypertension) and heart failure. It helps lower blood pressure by relaxing blood vessels, which makes it easier for the heart to pump blood. Epaned is also used to prevent heart attacks and strokes in certain high-risk patients. It comes in an oral solution form, making it especially suitable for children or patients who have difficulty swallowing tablets.
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Frequently Asked Questions
Can Epaned cause a cough?
Yes, Epaned and other ACE inhibitors are known to cause a dry cough in some patients.
Can I take Epaned during pregnancy?
No, Epaned should not be used during pregnancy as it can cause serious harm to the developing fetus.
How does Epaned lower blood pressure?
Epaned works by relaxing blood vessels and preventing the formation of angiotensin II, a substance that tightens blood vessels, thereby reducing blood pressure.
What should I do if I miss a dose?
If you miss a dose, take it as soon as you remember. If it’s almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double up doses.
Can Epaned cause kidney problems?
Yes, Epaned can affect kidney function, especially in patients with pre-existing kidney disease. Regular monitoring of kidney function is recommended.
Comprehensive Drug Guide
How Does Epaned Work?
Epaned works by inhibiting the angiotensin-converting enzyme (ACE), which results in the dilation of blood vessels and reduced levels of angiotensin II, a substance that causes blood vessels to tighten. This helps lower blood pressure and reduces strain on the heart in patients with heart failure.
Common Dosages
- Oral solution: 1 mg/mL
- Tablet: 2.5 mg, 5 mg, 10 mg, 20 mg
Typical Dosing
- For hypertension, the typical starting dose is 5 mg once daily, which can be adjusted based on response.
- For heart failure, the dose may start at 2.5 mg daily and be titrated up.
Typical Dosing
FDA Approved Indications
- Treatment of hypertension
- Treatment of heart failure
- Prevention of heart attacks and strokes in certain high-risk patients
Who Shouldn't Take Epaned?
- Known hypersensitivity to enalapril or any other ACE inhibitors
- History of angioedema
- Pregnancy (can cause harm to the fetus)
Advice From The Pharmacist
- Take Epaned at the same time each day, with or without food.
- Monitor your blood pressure regularly while taking Epaned to ensure it remains within a safe range.
- Stay hydrated, but avoid excessive salt intake, as it can counteract the effects of Epaned.
Side Effects of Epaned
Common Side Effects
- Cough
- Dizziness
- Fatigue
- Increased potassium levels (hyperkalemia)
Uncommon/Severe Side Effects
- Angioedema (swelling of the face, lips, or tongue)
- Kidney problems
- Low blood pressure (hypotension)
Risks and Warnings of Epaned
- Angioedema Risk: Epaned can cause angioedema, which can be life-threatening. Discontinue use immediately if you experience swelling.
- Pregnancy Risk: Epaned should not be used during pregnancy, as it can cause birth defects or harm to the fetus.
Interactions with Epaned
Common Drug Interactions
- Potassium supplements and potassium-sparing diuretics can increase the risk of hyperkalemia when taken with Epaned.
- NSAIDs: Nonsteroidal anti-inflammatory drugs may reduce the effectiveness of Epaned and increase the risk of kidney problems.
Alternatives to Epaned
- Lisinopril (another ACE inhibitor used for hypertension and heart failure)
- Losartan (an ARB, often used as an alternative to ACE inhibitors)
- Metoprolol (a beta-blocker used for heart failure)
