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Dymista
Dymista is a combination nasal spray containing azelastine hydrochloride (an antihistamine) and fluticasone propionate (a corticosteroid), used to treat seasonal allergic rhinitis (hay fever). It helps relieve symptoms such as sneezing, runny nose, itchy nose, and nasal congestion. The combination of an antihistamine and corticosteroid makes Dymista highly effective in controlling allergy symptoms and reducing inflammation in the nasal passages.
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Frequently Asked Questions
How long does it take for Dymista to start working?
Some patients may notice improvement within 30 minutes, but it may take a few days of regular use to achieve full symptom relief.
Can I use Dymista for long periods?
Yes, Dymista can be used for long-term management of allergy symptoms, but regular monitoring by a healthcare provider is recommended to avoid potential side effects.
Does Dymista cause drowsiness?
Yes, Dymista can cause drowsiness due to the azelastine component. Use caution when driving or operating heavy machinery.
Can I use Dymista with other allergy medications?
Consult your healthcare provider before using additional allergy medications, especially other nasal sprays, to avoid potential interactions or overuse.
What should I do if I miss a dose of Dymista?
If you miss a dose, take it as soon as you remember. If it’s close to the time of your next dose, skip the missed dose and take the next dose at the scheduled time. Do not double up on doses.
Comprehensive Drug Guide
How Does Dymista Work?
Dymista combines the actions of azelastine, which blocks the effects of histamine (a substance responsible for allergic reactions), and fluticasone, which reduces inflammation in the nasal passages. Together, they alleviate both allergic symptoms (sneezing, itching) and nasal congestion by reducing swelling and irritation in the nasal tissues.
Common Dosages
- Nasal spray: 137 mcg of azelastine and 50 mcg of fluticasone per spray
Typical Dosing
- The typical dosing for Dymista is one spray in each nostril twice daily. Shake the bottle well before each use, and ensure the nasal passages are clear before administering the spray.
Typical Dosing
FDA Approved Indications
- Seasonal allergic rhinitis in patients aged 6 years and older
Who Shouldn't Take Dymista?
- Known hypersensitivity to azelastine, fluticasone, or any components of the formulation
- Recent nasal surgery or injury, as the corticosteroid may slow healing
Advice From The Pharmacist
- Use Dymista regularly as prescribed to get the full benefit, especially during allergy season. It may take a few days to notice improvement.
- Shake the bottle before each use and prime the spray before the first use or if it hasn’t been used for several days.
- Avoid blowing your nose immediately after using Dymista to ensure the medication stays in the nasal passages.
- If using multiple nasal sprays, wait several minutes between each spray.
Side Effects of Dymista
Common Side Effects
- Bitter taste
- Nasal discomfort or dryness
- Headache
- Drowsiness
Uncommon/Severe Side Effects
- Nosebleeds
- Vision changes (rare, due to the corticosteroid)
- Increased risk of infections (e.g., fungal infections in the nose)
Risks and Warnings of Dymista
- Nasal Injury: The fluticasone component may delay wound healing if you have had recent nasal surgery or trauma.
- Systemic Corticosteroid Effects: Although rare, long-term use of Dymista may lead to systemic side effects like adrenal suppression or growth delay in children.
- Drowsiness: Azelastine, the antihistamine in Dymista, can cause drowsiness. Avoid activities requiring alertness (like driving) until you know how the medication affects you.
Interactions with Dymista
Common Drug Interactions
- Alcohol and sedatives: Combining Dymista with alcohol or sedatives can enhance the drowsiness caused by azelastine.
- CYP3A4 inhibitors (e.g., ketoconazole): These may increase the levels of fluticasone, raising the risk of side effects such as adrenal suppression.
- Other nasal corticosteroids: Avoid using other nasal corticosteroids with Dymista, as this can increase the risk of side effects like nasal irritation or nosebleeds.
Alternatives to Dymista
- Flonase (fluticasone propionate): A corticosteroid nasal spray for allergy relief.
- Nasacort (triamcinolone): Another corticosteroid nasal spray for allergy symptoms.
- Azelastine: Available as a standalone nasal spray for allergic rhinitis.
