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Droperidol
Droperidol is a medication often used in medical settings, primarily for its antiemetic (prevents vomiting) and sedative properties. Some common side effects include drowsiness, dizziness, and low blood pressure, but your healthcare team will carefully monitor these effects for you.
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Frequently Asked Questions
Can I take Droperidol before surgery?
Yes, Droperidol is often administered before or during surgery to produce calming effects or prevent postoperative nausea and vomiting.
Does Droperidol make you drowsy?
Yes, it's possible as it's often used for its calming effects.
What should I do if I experience severe side effects?
Contact your healthcare provider immediately or seek medical attention.
Comprehensive Drug Guide
How Does Droperidol Work?
FDA indications: Droperidol is primarily used to prevent nausea and vomiting associated with surgery and certain types of anesthesia. It's also used for producing calming effects before or during surgery.
Offlabel uses: Although rare, it might be used for treatmentresistant schizophrenia or other cases of severe agitation.
What is Droperidol Used For?
Injection: 2.5mg/ml
Common Dosages
For nausea/vomiting ? Adults may receive 0.625mg to 1.25mg as a single injection before surgery.
Typical Dosing
FDA Approved Indications
- For calming effects, adults may receive 2.5mg to 10mg injections as per their health and required effects.
Off-Label Uses
- Have a known hypersensitivity to Droperidol or other butyrophenones.
- Have been diagnosed with a condition leading to a prolonged QT interval.
- Have Parkinson's disease
Who Shouldn't Take Droperidol?
- Typically administered in a hospital or clinical setting, so the healthcare professionals will provide instructions as needed.
- Your medical team will monitor you for potential side effects.
- Alert your healthcare provider immediately if you feel an uncontrolled movement, intense restlessness, or have any drastic mood changes.
Advice From The Pharmacist
- You might feel lightheaded or drowsy, avoid operating heavy machinery until you know how Droperidol affects you.
- You might experience headaches or changes in your mood.
- You may have a dry mouth or a stuffy nose.
Side Effects of Droperidol
Common Side Effects
- Uncommon side effects:
- You might have some swelling or redness at the injection site.
- You might experience constipation.
- You might feel anxious or confused at times.
- Rare side effects:
- You might notice some changes in your heart rhythm, so inform your doctor immediately.
- You might have a fever or flulike symptoms.
- You might experience significant changes in your mood or behavior.
- Severe side effects:
- If you experience severe lightheadedness, fainting, or slow or fast heartbeat, these are serious and you should get immediate medical help.
- If you have muscle stiffness or uncontrolled movements, especially of your face, lips, tongue, or throat, seek immediate medical attention.
- Signs of a serious allergic reaction like rash, itching or swelling of the face/tongue/throat, severe dizziness, or trouble breathing need immediate medical attention.
Uncommon/Severe Side Effects
- Droperidol can cause severe cardiacrelated effects, including a prolonged QT interval which can result in serious heart rhythm disturbances.
- It's not advisable to use if you have Parkinson's disease, as it may exacerbate symptoms.
- It can interact with certain medications leading to increased sedation and additive effects on heart rhythm.
Risks and Warnings of Droperidol
- Anxiolytics
- Sedative hypnotics
- Opioids
- Antiarrhythmics
- Antipsychotics
- Certain antibiotics
Interactions with Droperidol
Common Drug Interactions
- Avoid alcohol and grapefruit juice
Alternatives to Droperidol
- Phenothiazines
- Antihistamines
- Benzodiazepines
- Metoclopramide
