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Dermetazole
Dermetazole (clotrimazole and betamethasone dipropionate) is a topical antifungal and corticosteroid combination medication used to treat fungal infections of the skin, such as ringworm, athlete’s foot, and jock itch. The combination of clotrimazole, an antifungal, and betamethasone, a corticosteroid, helps to reduce fungal growth while also relieving inflammation, redness, and itching.
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Frequently Asked Questions
How long does it take for Dermetazole to work?
You should see improvement in symptoms such as itching and redness within a few days, but full treatment may take 2 to 4 weeks, depending on the infection.
Can Dermetazole be used on the face?
Dermetazole should not be used on the face unless specifically directed by a healthcare provider, as the skin on the face is more prone to side effects like thinning and discoloration.
What should I do if I miss a dose of Dermetazole?
Apply the missed dose as soon as you remember. If it’s close to your next scheduled dose, skip the missed dose and continue with your regular schedule. Do not double up doses.
Can I use Dermetazole for other types of skin infections?
Dermetazole is specifically indicated for fungal infections like athlete’s foot, ringworm, and jock itch. It should not be used for bacterial or viral infections.
Is Dermetazole safe for long-term use?
Dermetazole is intended for short-term use to treat fungal infections. Long-term use, especially of the corticosteroid component, can lead to skin thinning and other side effects.
Comprehensive Drug Guide
How Does Dermetazole Work?
Dermetazole works by combining the antifungal properties of clotrimazole, which inhibits the growth of fungi by altering their cell membranes, with the anti-inflammatory effects of betamethasone, which reduces swelling, itching, and redness associated with fungal infections.
Common Dosages
- Topical cream: 1% clotrimazole and 0.05% betamethasone.
Typical Dosing
- Apply a thin layer of Dermetazole to the affected area twice daily (morning and evening). Use for two weeks for tinea cruris and tinea corporis, or four weeks for tinea pedis, or as directed by your healthcare provider.
Typical Dosing
FDA Approved Indications
- Tinea pedis (athlete’s foot)
- Tinea cruris (jock itch)
- Tinea corporis (ringworm)
Who Shouldn't Take Dermetazole?
- Known hypersensitivity to clotrimazole, betamethasone, or any component of the formulation.
- Viral skin infections, such as herpes simplex or chickenpox.
Advice From The Pharmacist
- Apply Dermetazole to clean, dry skin and avoid covering the treated area with bandages or dressings unless directed by your healthcare provider.
- Do not use Dermetazole for longer than recommended, as overuse of corticosteroids can lead to thinning of the skin.
- If the infection does not improve within the recommended treatment time, contact your healthcare provider for further evaluation.
Side Effects of Dermetazole
Common Side Effects
- Burning
- Itching
- Redness
- Dryness
Uncommon/Severe Side Effects
- Skin thinning (atrophy)
- Stretch marks
- Increased susceptibility to infections
Risks and Warnings of Dermetazole
- Skin Atrophy: Prolonged use of betamethasone can cause thinning of the skin, stretch marks, or discoloration. Do not use Dermetazole for longer than prescribed.
- Overuse of Corticosteroids: Overuse can lead to systemic absorption, resulting in side effects such as high blood sugar or suppressed adrenal gland function.
Interactions with Dermetazole
Common Drug Interactions
- Other topical corticosteroids: Using other corticosteroid-containing products alongside Dermetazole can increase the risk of skin thinning or systemic absorption.
- Occlusive dressings: Avoid using occlusive dressings over the treated area, as this can increase the absorption of the corticosteroid and lead to side effects.
Alternatives to Dermetazole
- Lotrisone: A similar antifungal and corticosteroid combination cream used to treat fungal skin infections.
- Lamisil (terbinafine): A topical antifungal cream used to treat various fungal infections, without the corticosteroid component.
- Clotrimazole: Available as a standalone antifungal cream for the treatment of tinea infections.
