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Dermazene

Dermazene is a combination topical corticosteroid and antifungal/antibacterial medication used to treat various inflammatory skin conditions that may involve infection. It contains hydrocortisone, a corticosteroid that reduces inflammation, and iodoquinol, which has antimicrobial properties to treat fungal and bacterial infections. Dermazene is often prescribed for conditions like eczema, dermatitis, and infected skin rashes.



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Frequently Asked Questions

How long should I use Dermazene?
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The duration of use will depend on the severity of your condition. Typically, it should not be used for more than 2 weeks without consulting your healthcare provider.

Can Dermazene be used for fungal infections?
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Yes, Dermazene contains iodoquinol, which has antifungal properties. It is used to treat skin infections caused by fungi, bacteria, or both.

What should I do if I miss a dose of Dermazene?
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Apply the missed dose as soon as you remember. If it’s close to the next application, skip the missed dose and continue with your regular schedule. Do not double up on doses.

Can I use Dermazene on my face?
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While Dermazene can be used on the face, caution should be exercised, especially with long-term use, as hydrocortisone can cause skin thinning and other side effects.

Is Dermazene safe for children?
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Dermazene may be used in children, but it should be applied sparingly and only as directed by a healthcare provider. Long-term use in children should be avoided to prevent side effects such as skin thinning.

Comprehensive Drug Guide

How Does Dermazene Work?

Dermazene works by combining the anti-inflammatory effects of hydrocortisone, which helps reduce redness, swelling, and itching, with the antimicrobial action of iodoquinol, which kills or inhibits the growth of fungi and bacteria. Together, these components address both the inflammation and infection associated with certain skin conditions.



Common Dosages

  • Hydrocortisone 1%
  • Iodoquinol 1%

Typical Dosing

  • For inflammatory skin conditions: Apply a thin layer of Dermazene cream to the affected area 2 to 4 times daily or as directed by your healthcare provider.


Typical Dosing

FDA Approved Indications

  • Eczema
  • Seborrheic dermatitis
  • Contact dermatitis
  • Infected skin rashes
  • Other mixed inflammatory and infectious skin conditions


Who Shouldn't Take Dermazene?

  • Known hypersensitivity to hydrocortisone, iodoquinol, or any components of the formulation
  • Viral skin infections, such as herpes simplex or varicella (chickenpox)


Advice From The Pharmacist

  • Apply Dermazene cream sparingly to the affected area and rub it in gently. Do not use more than prescribed, as overuse can lead to side effects.
  • Avoid prolonged use or application over large areas, as this can lead to systemic absorption of corticosteroids, increasing the risk of side effects.
  • Wash your hands before and after applying the cream, and avoid getting the medication in your eyes or mouth.


Side Effects of Dermazene

Common Side Effects

  • Mild burning or stinging at the application site
  • Skin dryness or irritation


Uncommon/Severe Side Effects

  • Skin thinning (with prolonged use)
  • Allergic reactions
  • Systemic corticosteroid effects, such as increased blood sugar or high blood pressure, with excessive use


Risks and Warnings of Dermazene

  • Skin Thinning: Prolonged use of corticosteroids like hydrocortisone can lead to thinning of the skin, especially in sensitive areas like the face.
  • Systemic Absorption: Using Dermazene on large areas of the body or for long periods can result in systemic absorption of corticosteroids, leading to side effects such as adrenal suppression.


Interactions with Dermazene

Common Drug Interactions

  • Other topical medications: Avoid using Dermazene with other topical corticosteroids or antifungals without consulting your healthcare provider, as this may increase the risk of side effects.
  • Systemic corticosteroids: If you are taking oral corticosteroids, using Dermazene topically can increase the risk of systemic corticosteroid effects.


Alternatives to Dermazene

  • Clotrimazole/Betamethasone cream: A combination of antifungal and corticosteroid for treating fungal infections with inflammation.
  • Nystatin/Triamcinolone cream: Another antifungal and corticosteroid combination for fungal infections with skin inflammation.
  • Hydrocortisone cream: A standalone corticosteroid for treating inflammation without infection.