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Delyla

Delyla (desogestrel and ethinyl estradiol) is a combination oral contraceptive used to prevent pregnancy. It contains two hormones: desogestrel (a progestin) and ethinyl estradiol (an estrogen). Delyla works by preventing ovulation, thickening cervical mucus to block sperm from reaching the egg, and altering the uterine lining to prevent implantation of a fertilized egg.



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Frequently Asked Questions

How effective is Delyla at preventing pregnancy?
Open FAQClose FAQ

When taken correctly, Delyla is over 99% effective at preventing pregnancy. However, missing doses or taking the pills inconsistently may lower its effectiveness.

Can I use Delyla to skip my period?
Open FAQClose FAQ

Yes, some women choose to skip the inactive pills and start a new pack of active pills right away to avoid having a period. Consult your healthcare provider for advice on how to do this safely.

What should I do if I miss a pill?
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If you miss one active pill, take it as soon as you remember. If you miss two or more active pills, follow the instructions in the package insert, and use a backup method of contraception.

Can Delyla cause weight gain?
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Some women may experience mild weight gain due to fluid retention, but significant weight gain is uncommon.

Is it safe to use Delyla for long-term contraception?
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Yes, Delyla is safe for long-term use, but regular check-ups with your healthcare provider are recommended to monitor for any potential side effects.

Comprehensive Drug Guide

How Does Delyla Work?

  • Inhibiting ovulation (the release of an egg from the ovaries).
  • Thickening cervical mucus, making it difficult for sperm to enter the uterus.
  • Altering the uterine lining, making it less likely for a fertilized egg to implant.


Common Dosages

  • Oral tablets: 28-day pack (21 active pills containing hormones and 7 inactive pills).

Typical Dosing

  • Take one tablet daily at the same time every day for 28 days: 21 active hormone pills followed by 7 inactive pills, during which you will have a withdrawal bleed (your period).


Typical Dosing

FDA Approved Indications

  • Pregnancy in women who choose oral contraceptives as their method of birth control.


Who Shouldn't Take Delyla?

  • Known hypersensitivity to desogestrel, ethinyl estradiol, or any component of the formulation.
  • Blood clots, heart attack, or stroke.
  • Breast cancer or other estrogen- or progestin-sensitive cancers.
  • Liver disease or tumors.


Advice From The Pharmacist

  • Take Delyla at the same time every day, preferably with food, to reduce the chance of nausea.
  • If you miss a dose, take it as soon as you remember. If you miss two or more doses, follow the instructions in the package insert or consult your healthcare provider, as additional contraception may be required.
  • Use a backup method of contraception (e.g., condoms) if you miss pills or start a new pack late.


Side Effects of Delyla

Common Side Effects

  • Nausea
  • Breast tenderness
  • Headache
  • Spotting or breakthrough bleeding
  • Mood changes


Uncommon/Severe Side Effects

  • Blood clots (deep vein thrombosis, pulmonary embolism)
  • Stroke
  • Liver problems (jaundice)
  • High blood pressure


Risks and Warnings of Delyla

  • Blood Clots: Combination birth control pills like Delyla can increase the risk of blood clots, especially in smokers and women over 35 years of age.
  • Cancer Risk: Long-term use of hormonal contraceptives may increase the risk of breast cancer and cervical cancer. Regular screenings are recommended.
  • Smoking: Smoking while using Delyla significantly increases the risk of serious cardiovascular events, such as heart attack or stroke.


Interactions with Delyla

Common Drug Interactions

  • Antibiotics (e.g., rifampin) and anticonvulsants (e.g., carbamazepine) can reduce the effectiveness of Delyla, increasing the risk of pregnancy.
  • St. John’s Wort: This herbal supplement can decrease the effectiveness of birth control pills and should be avoided while using Delyla.
  • Anticoagulants: Hormonal contraceptives may reduce the effectiveness of blood thinners like warfarin.


Alternatives to Delyla

  • Yaz: Another combination oral contraceptive that contains drospirenone and ethinyl estradiol.
  • Ortho Tri-Cyclen: A combination pill containing norgestimate and ethinyl estradiol, often prescribed for both contraception and acne management.
  • NuvaRing: A contraceptive vaginal ring that releases hormones similar to those in Delyla, but with a different route of administration.