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Daysee

Daysee (levonorgestrel and ethinyl estradiol) is an extended-cycle oral contraceptive used to prevent pregnancy. It contains two hormones: levonorgestrel (a progestin) and ethinyl estradiol (an estrogen). Daysee is designed for women who prefer fewer menstrual cycles, with active hormone pills taken for 84 days followed by 7 days of inactive pills, resulting in a period every three months.



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Frequently Asked Questions

How effective is Daysee at preventing pregnancy?
Open FAQClose FAQ

When taken correctly, Daysee is over 99% effective at preventing pregnancy. Missing doses or taking the pills inconsistently may lower its effectiveness.

Can I use Daysee to skip my period?
Open FAQClose FAQ

Yes, Daysee is specifically designed to reduce the number of menstrual periods to once every three months. Some women may experience spotting or breakthrough bleeding during the first few cycles.

What should I do if I miss a pill?
Open FAQClose FAQ

If you miss one active pill, take it as soon as you remember. If you miss two or more active pills, follow the instructions in the package insert, and use a backup method of contraception.

Can Daysee cause weight gain?
Open FAQClose FAQ

Some women may experience mild weight gain due to fluid retention, but significant weight gain is uncommon.

Is it safe to use Daysee for long-term contraception?
Open FAQClose FAQ

Yes, Daysee is safe for long-term use, but regular check-ups with your healthcare provider are recommended to monitor for any potential side effects.

Comprehensive Drug Guide

How Does Daysee Work?

  • Inhibiting ovulation (preventing the release of an egg from the ovaries).
  • Thickening cervical mucus, making it difficult for sperm to enter the uterus.
  • Altering the uterine lining, making it less likely for a fertilized egg to implant.


Common Dosages

  • Oral tablets: 84 active tablets containing 0.15 mg of levonorgestrel and 0.03 mg of ethinyl estradiol, and 7 inactive (placebo) tablets.

Typical Dosing

  • Take one tablet daily at the same time every day for 91 days: 84 active hormone pills followed by 7 inactive pills, during which you will have a period.


Typical Dosing

FDA Approved Indications

  • Prevention of pregnancy in women who choose an extended-cycle birth control pill, which reduces the frequency of menstrual periods.


Who Shouldn't Take Daysee?

  • Known hypersensitivity to levonorgestrel, ethinyl estradiol, or any component of the formulation.
  • Blood clots, heart attack, or stroke.
  • Breast cancer or other estrogen- or progestin-sensitive cancers.
  • Liver disease or liver tumors.


Advice From The Pharmacist

  • Take Daysee at the same time every day, preferably with food, to reduce the chance of nausea.
  • If you miss a dose, take it as soon as you remember. If you miss two or more doses, follow the instructions in the package insert or consult your healthcare provider, as additional contraception may be required.
  • Use a backup method of contraception (e.g., condoms) if you miss pills or start a new pack late.

Side Effects of Daysee

Common Side Effects

  • Nausea
  • Breast tenderness
  • Headache
  • Spotting or breakthrough bleeding
  • Mood changes


Uncommon/Severe Side Effects

  • Blood clots (deep vein thrombosis, pulmonary embolism)
  • Stroke
  • Liver problems (jaundice)
  • High blood pressure


Risks and Warnings of Daysee

  • Blood Clots: Extended-cycle combination birth control pills like Daysee can increase the risk of blood clots, especially in smokers and women over 35 years of age.
  • Cancer Risk: Long-term use of hormonal contraceptives may increase the risk of breast cancer and cervical cancer. Regular screenings are recommended.
  • Smoking: Smoking while using Daysee significantly increases the risk of serious cardiovascular events, such as heart attack or stroke.


Interactions with Daysee

Common Drug Interactions

  • Antibiotics (e.g., rifampin) and anticonvulsants (e.g., carbamazepine) can reduce the effectiveness of Daysee, increasing the risk of pregnancy.
  • St. John’s Wort: This herbal supplement can decrease the effectiveness of birth control pills and should be avoided while using Daysee.
  • Anticoagulants: Hormonal contraceptives may reduce the effectiveness of blood thinners like warfarin.


Alternatives to Daysee

  • Seasonique: Another extended-cycle oral contraceptive that provides continuous dosing with fewer periods.
  • LoSeasonique: A lower-dose alternative for extended-cycle contraception with fewer hormonal side effects.
  • Mirena: A hormonal intrauterine device (IUD) that provides long-term contraception with fewer menstrual periods.