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Cytomel

Cytomel (generic name: liothyronine sodium) is a synthetic form of the thyroid hormone T3 (triiodothyronine) used to treat hypothyroidism, a condition where the thyroid gland does not produce enough thyroid hormone. It is also used for treating or preventing goiter and can be used in combination with other thyroid medications. By replacing or supplementing T3, Cytomel helps restore normal metabolism, energy levels, and overall health in individuals with thyroid hormone deficiency.



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Frequently Asked Questions

How long does it take for Cytomel to start working?
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Most patients begin to notice improvements in symptoms within a few days to a week, but full effects may take several weeks as the dosage is adjusted.

Can Cytomel be taken with other thyroid medications?
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Yes, Cytomel is sometimes taken in combination with levothyroxine (T4 hormone) to optimize thyroid hormone levels. Always follow your doctor's guidance.

What should I do if I miss a dose of Cytomel?
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Take the missed dose as soon as you remember. If it’s close to the next dose, skip the missed dose and resume your regular schedule. Do not double up.

Can Cytomel cause weight loss?
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Cytomel may cause some weight loss as it helps normalize metabolism in hypothyroid patients. However, it should not be used as a weight-loss medication.

Is Cytomel safe during pregnancy?
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Yes, thyroid hormone replacement is usually necessary during pregnancy to maintain normal thyroid function. However, always consult your doctor to ensure the correct dosage.

Comprehensive Drug Guide

How Does Cytomel Work?

Cytomel works by providing triiodothyronine (T3), a crucial thyroid hormone that regulates metabolism, energy production, and protein synthesis in the body. It compensates for the thyroid’s inability to produce sufficient T3, thereby normalizing thyroid hormone levels and helping restore normal metabolic function.



Common Dosages

  • 5 mcg tablets
  • 25 mcg tablets
  • 50 mcg tablets

Typical Dosing

  • For hypothyroidism: The usual starting dose is 25 mcg once daily, with the dose being adjusted by your healthcare provider based on your response. The dose may be increased by 12.5 to 25 mcg every 1 to 2 weeks until the desired effect is achieved, with a typical maintenance dose ranging from 25 to 75 mcg daily.


Typical Dosing

FDA Approved Indications

  • Hypothyroidism (T3 deficiency)
  • Goiter (enlarged thyroid)
  • As part of thyroid suppression testing to diagnose thyroid function issues


Who Shouldn't Take Cytomel?

  • Untreated adrenal insufficiency
  • Known hypersensitivity to liothyronine or any ingredients in the formulation


Advice From The Pharmacist

  • Take Cytomel once daily, preferably in the morning, with or without food. It’s important to take it at the same time each day.
  • Do not stop taking Cytomel without consulting your doctor, as abrupt discontinuation can result in worsening hypothyroidism symptoms.
  • Regular monitoring of thyroid hormone levels is important to ensure the dosage is optimal.


Side Effects of Cytomel

Common Side Effects

  • Weight loss
  • Nervousness or irritability
  • Sweating
  • Headache
  • Increased heart rate


Uncommon/Severe Side Effects

  • Chest pain or palpitations
  • Irregular heartbeat
  • Shortness of breath


Risks and Warnings of Cytomel

  • Heart-Related Risks: Cytomel can increase heart rate and may cause chest pain or irregular heart rhythms, particularly in individuals with heart disease. Monitoring is essential.
  • Bone Loss: Long-term use of high doses of Cytomel can lead to bone thinning (osteoporosis), especially in postmenopausal women.


Interactions with Cytomel

Common Drug Interactions

  • Anticoagulants: Cytomel may enhance the effects of blood-thinning medications like warfarin, increasing the risk of bleeding.
  • Diabetes medications: Cytomel may reduce the effectiveness of insulin or oral diabetes medications, necessitating adjustments to your diabetes treatment.
  • Cholestyramine: This medication can reduce the absorption of Cytomel when taken together.


Alternatives to Cytomel

  • Levothyroxine: A synthetic form of T4, another thyroid hormone, which is commonly used to treat hypothyroidism.
  • Armour Thyroid: A natural desiccated thyroid hormone that contains both T3 and T4.
  • Euthyrox: Another form of levothyroxine for thyroid hormone replacement.