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Cyclogyl

Cyclogyl (cyclopentolate hydrochloride) is a mydriatic and cycloplegic agent used to dilate the pupil and temporarily paralyze the eye's focusing muscles. It is commonly used during eye exams, particularly to examine the retina, and in other ophthalmic procedures. Cyclogyl helps healthcare providers get a clear view of the back of the eye for diagnostic purposes.



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Frequently Asked Questions

How long do the effects of Cyclogyl last?
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The effects of Cyclogyl typically last for 4 to 24 hours, depending on the concentration used. In rare cases, effects can last longer, especially in young children or elderly patients.

Can I drive after using Cyclogyl?
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No, you should not drive or operate heavy machinery until the effects of Cyclogyl wear off. The drops cause blurred vision and light sensitivity, which can impair your ability to drive safely.

Is Cyclogyl safe for children?
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Yes, Cyclogyl is commonly used in children for eye exams and determining their prescription (cycloplegic refraction). However, children are more susceptible to side effects, so careful dosing is essential.

Can Cyclogyl be used for routine eye exams?
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Yes, Cyclogyl is often used during routine eye exams to dilate the pupils and allow for a thorough examination of the retina and other structures at the back of the eye.

What should I do if I experience prolonged blurred vision after using Cyclogyl?
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If your vision remains blurred for more than 24 hours, contact your eye doctor. While temporary blurred vision is normal after using Cyclogyl, prolonged effects may require medical attention.

Comprehensive Drug Guide

How Does Cyclogyl Work?

Cyclogyl works by blocking the action of acetylcholine on the muscles of the eye. This causes the pupil to dilate (mydriasis) and the ciliary muscles that control focusing to relax (cycloplegia), temporarily paralyzing the eye's ability to focus.



Common Dosages

  • Ophthalmic solution (eye drops): 0.5%, 1%, and 2%.

Typical Dosing

  • For pupil dilation or cycloplegic refraction: One to two drops of 0.5% to 2% solution are instilled into the eye, repeated after 5 to 10 minutes if needed. The effects typically last for several hours.


Typical Dosing

FDA Approved Indications

  • Pupil dilation during eye examinations.
  • Cycloplegic refraction: Temporarily paralyzing the focusing muscles to determine a person's correct prescription.


Who Shouldn't Take Cyclogyl?

  • Known hypersensitivity to cyclopentolate or any component of the formulation.
  • Narrow-angle glaucoma or untreated increased intraocular pressure.


Advice From The Pharmacist

  • Avoid driving or operating heavy machinery after using Cyclogyl, as it causes temporary blurred vision and light sensitivity. These effects may last several hours.
  • Protect your eyes from bright light by wearing sunglasses, as your pupils will remain dilated for some time after using the drops.
  • Do not touch the tip of the dropper to your eye or any surface, as this can contaminate the solution.


Side Effects of Cyclogyl

Common Side Effects

  • Blurred vision
  • Light sensitivity (photophobia)
  • Stinging or burning in the eyes
  • Dry mouth


Uncommon/Severe Side Effects

  • Increased intraocular pressure (in individuals with glaucoma)
  • Severe allergic reactions (rash, swelling, difficulty breathing)
  • Hallucinations (mostly in young children with overuse)


Risks and Warnings of Cyclogyl

  • Narrow-angle Glaucoma Risk: Cyclogyl can worsen narrow-angle glaucoma, leading to a dangerous increase in eye pressure. It is contraindicated in patients with this condition.
  • Light Sensitivity: Since Cyclogyl causes prolonged pupil dilation, patients may experience sensitivity to light for several hours after use. Sunglasses are recommended during this period.


Interactions with Cyclogyl

Common Drug Interactions

  • Anticholinergic medications: Using other anticholinergic medications (e.g., atropine) with Cyclogyl may increase the risk of side effects, such as blurred vision, dry mouth, and difficulty urinating.
  • Glaucoma medications: Cyclogyl should not be used in combination with glaucoma medications unless directed by an ophthalmologist, as it can increase eye pressure.


Alternatives to Cyclogyl

  • Atropine eye drops: Another mydriatic and cycloplegic agent used for similar purposes, such as eye examinations or cycloplegic refraction.
  • Tropicamide (Mydriacyl): A shorter-acting mydriatic used to dilate the pupil during eye exams.
  • Phenylephrine: A mydriatic agent used for pupil dilation without causing cycloplegia (paralysis of the focusing muscles).