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Crestor
Rosuvastatin is a type of medication known as a statin or HMG-CoA reductase inhibitor. It's used to lower cholesterol and fats (triglycerides) in the blood, helping reduce the risk of heart disease, strokes, and heart attacks. Some common side effects might include muscle or joint pain, constipation, and nausea, but usually, the benefits of these issues.
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Frequently Asked Questions
Can I take rosuvastatin if I have liver disease?
It's best to avoid rosuvastatin if you have active liver disease. Always discuss this with your doctor.
Does rosuvastatin have any food interactions?
Grapefruit juice may increase the amount of rosuvastatin in your body. Stay clear of it while taking this medication.
I missed a dose of rosuvastatin, what should I do?
Take it as soon as you remember, unless it's close to the time for your next dose. Never take extra doses.
What should I do if I experience muscle weakness or pain?
Contact your doctor urgently. This could be a sign of a rare but serious side effect.
Comprehensive Drug Guide
How Does Crestor Work?
Rosuvastatin is a selective and competitive inhibitor of the HMG-CoA reductase enzyme, which is responsible for converting HMG-CoA to mevalonate, a precursor of cholesterol. By limiting cholesterol biosynthesis, rosuvastatin lowers hepatic cholesterol levels which prompts an increase in uptake of LDL cholesterol.
What is Crestor Used For?
FDA indications: Rosuvastatin is used to lower cholesterol and triglycerides (fatty substances) in the blood. It's also used to slow the progression of atherosclerosis and decrease the risk of heart attacks, strokes, and revascularization procedures.
Off-label uses: It's used to treat familial hypercholesterolemia and help prevent
Common Dosages
Tablets: 5mg, 10mg, 20mg, 40mg
Typical Dosing
FDA Approved Indications
- For FDA-approved indications:
- High cholesterol: 5 to 40mg once daily.
- Atherosclerosis: 20 to 40mg once daily.
- For off-label uses:
- Familial hypercholesterolemia: 5 to 40mg once daily.
- Prevention of cardiovascular disease: 5 to 20mg once daily.
Who Shouldn't Take Crestor?
- Have liver disease or high liver enzymes.
- Pregnant, planning to become pregnant, or breastfeeding.
- Rosuvastatin can harm an unborn baby.
- Have a history of a severe allergic reaction to rosuvastatin or any other statin.
- Drinking more than 2 alcoholic drinks daily.
- Taking medications that interact with rosuvastatin.
Advice From The Pharmacist
- Take rosuvastatin once daily at the same time.
- It can be taken with or without food.
- Avoid drinking grapefruit juice while taking this medication.
- Contact your doctor immediately if you have unexplained pain, tenderness, or weakness in your muscles, especially if you also have a fever or are feeling ill.
- Pregnant or breastfeeding women should not take this drug.
- Check your cholesterol levels every 3-6 months.
Side Effects of Crestor
Common Side Effects
- You might have muscle or joint pain.
- You might experience constipation.
- You might have nausea.
- You might feel weak or tired.
Uncommon/Severe Side Effects
- Rare side effects:
- You may develop liver problems.
- You might have a muscle problem called rhabdomyolysis.
- Severe side effects:
- Signs of a serious allergic reaction like rash, itching or swelling of the face/tongue/throat, severe dizziness, or trouble breathing need immediate medical attention.
Risks and Warnings of Crestor
- Individuals with liver disease should not use rosuvastatin due to the increased risk of liver damage.
- If you drink large amounts of alcohol, consult with your healthcare provider about the safety of using this medication.
- Rosuvastatin has the potential to cause muscle problems, which can be more likely in older adults and individuals with kidney disease.
- Patients should monitor their blood sugar levels carefully as Rosuvastatin could affect blood sugar control.
- If pregnant or considering pregnancy, rosuvastatin should not be taken due to associated risks with fetal development.
Interactions with Crestor
Common Drug Interactions
- Other cholesterol drugs
- Certain HIV drugs
- Certain hepatitis C drugs
- Warfarin
- Birth control pills
- Antacids
Alternatives to Crestor
- Atorvastatin
- Simvastatin
- Pravastatin
- Fluvastatin
- Pitavastatin