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CoreMino
CoreMino (minocycline hydrochloride) is a tetracycline antibiotic used to treat bacterial infections, including acne, respiratory tract infections, urinary tract infections, and certain skin infections. It is often prescribed for patients with moderate to severe acne due to its anti-inflammatory and antibacterial properties. CoreMino works by inhibiting the growth and spread of bacteria.
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Frequently Asked Questions
How long does it take for CoreMino to work for acne?
It may take several weeks to notice significant improvements in acne symptoms. Continue using the medication as prescribed, even if results are not immediate.
Can CoreMino be used in children?
CoreMino is not recommended for use in children under the age of 8 years, as it can cause permanent tooth discoloration and affect bone development.
What should I do if I miss a dose of CoreMino?
If you miss a dose, take it as soon as you remember. If it’s close to your next scheduled dose, skip the missed dose and continue with your regular schedule. Do not double up on doses.
Can CoreMino cause dizziness?
Yes, dizziness is a common side effect of CoreMino. If dizziness occurs, avoid driving or operating heavy machinery until the sensation subsides.
Is CoreMino safe to take during pregnancy?
No, CoreMino is not safe during pregnancy due to the risk of harm to the developing fetus, including tooth discoloration and bone development issues.
Comprehensive Drug Guide
How Does CoreMino Work?
CoreMino works by inhibiting bacterial protein synthesis by binding to the 30S ribosomal subunit of bacteria. This action prevents the production of essential proteins needed for bacterial growth and replication, ultimately stopping the spread of infection.
Common Dosages
- Oral capsules: 50 mg, 75 mg, 100 mg
Typical Dosing
- For acne: The typical dose is 50 to 100 mg orally twice daily.
- For bacterial infections: The dose is usually 100 mg every 12 hours, depending on the severity and type of infection.
Typical Dosing
FDA Approved Indications
- Acne vulgaris
- Respiratory tract infections (e.g., bronchitis)
- Urinary tract infections (UTIs)
- Skin infections
- Other bacterial infections caused by susceptible organisms
Who Shouldn't Take CoreMino?
- Known hypersensitivity to minocycline, tetracyclines, or any component of the formulation.
- Pregnancy: Minocycline can cause harm to the developing fetus, including permanent tooth discoloration and bone development issues.
Advice From The Pharmacist
- Take CoreMino with a full glass of water to avoid irritation of the esophagus. Avoid lying down immediately after taking the medication.
- Avoid prolonged exposure to sunlight or tanning beds, as minocycline can make your skin more sensitive to the sun (photosensitivity).
- Do not take CoreMino with antacids, calcium supplements, or iron products within 2 hours of each dose, as these can reduce the absorption of the medication.
Side Effects of CoreMino
Common Side Effects
- Nausea
- Dizziness
- Diarrhea
- Tooth discoloration (especially in children)
- Photosensitivity
Uncommon/Severe Side Effects
- Severe allergic reactions (rash, swelling, difficulty breathing)
- Liver toxicity
- Intracranial hypertension (headaches, vision problems)
- Autoimmune conditions (drug-induced lupus, hepatitis)
Risks and Warnings of CoreMino
- Tooth Discoloration: CoreMino can cause permanent tooth discoloration if used in children under the age of 8 or during pregnancy.
- Photosensitivity: CoreMino can make the skin more sensitive to sunlight, increasing the risk of sunburn. Use sunscreen and protective clothing when outdoors.
- Liver Toxicity: Minocycline can cause liver damage in rare cases. Regular monitoring of liver function may be required for long-term use.
Interactions with CoreMino
Common Drug Interactions
- Antacids, calcium, and iron supplements: These can interfere with the absorption of minocycline, reducing its effectiveness. Take these products at least 2 hours apart from CoreMino.
- Isotretinoin (Accutane): Combining CoreMino with isotretinoin increases the risk of intracranial hypertension (increased pressure in the skull).
- Oral contraceptives: CoreMino may reduce the effectiveness of hormonal birth control. Consider using an additional form of contraception while on this medication.
Alternatives to CoreMino
- Doxycycline: Another tetracycline antibiotic used for similar infections, including acne, with fewer side effects like dizziness.
- Clindamycin: An antibiotic used for skin infections and acne, often in topical form for acne treatment.
- Azithromycin: A macrolide antibiotic used to treat respiratory and skin infections.
