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Cordran
Cordran (flurandrenolide) is a medium- to high-potency topical corticosteroid used to treat inflammatory skin conditions such as eczema, dermatitis, and psoriasis. It helps reduce symptoms like redness, itching, and swelling by suppressing the immune response in the skin. Cordran is available in various forms and is generally prescribed for short-term use to manage flare-ups.
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Frequently Asked Questions
How long does it take for Cordran to work?
Most people notice improvement in skin inflammation and itching within a few days of starting treatment with Cordran. However, full effects may take up to 1 to 2 weeks.
Can I use Cordran on my face?
Cordran should not be used on the face unless specifically directed by your healthcare provider, as it can cause thinning of the skin in this sensitive area.
What should I do if I miss a dose of Cordran?
If you miss a dose, apply it as soon as you remember. If it is close to your next scheduled dose, skip the missed dose and continue with your regular schedule. Do not double up doses.
Can Cordran be used for long-term treatment?
No, Cordran is usually prescribed for short-term use. Long-term use increases the risk of side effects such as skin thinning and adrenal suppression. Your healthcare provider will guide you on how long to use it.
Is Cordran Tape better than cream or ointment?
Cordran Tape provides continuous delivery of the medication and may be more convenient for certain areas of the body. However, the choice between tape and other forms depends on the location and severity of the condition.
Comprehensive Drug Guide
How Does Cordran Work?
Cordran works by reducing inflammation and suppressing the immune response in the skin. It inhibits the release of inflammatory chemicals like prostaglandins and histamines, helping to alleviate redness, swelling, and itching in conditions such as eczema and psoriasis.
Common Dosages
- Cream, ointment, lotion: 0.05%
- Cordran Tape: A medicated tape that delivers a constant dose of flurandrenolide over time.
Typical Dosing
- For inflammatory skin conditions: Apply a thin layer of cream, ointment, or lotion to the affected area two to four times daily, or as directed by your healthcare provider.
- For Cordran Tape: Apply the tape to the affected area and change it every 12 to 24 hours, as instructed.
Typical Dosing
FDA Approved Indications
- Eczema
- Psoriasis
- Dermatitis
- Other inflammatory skin conditions
Who Shouldn't Take Cordran?
- Known hypersensitivity to flurandrenolide or other components of the formulation.
- Untreated skin infections, including bacterial, fungal, or viral infections.
Advice From The Pharmacist
- Avoid applying Cordran to the face, groin, or underarms unless specifically directed by your healthcare provider.
- Do not use Cordran on areas with broken or infected skin unless prescribed for that condition.
- If using Cordran Tape, ensure the skin is clean and dry before application, and do not apply the tape to large areas of the skin.
- Wash your hands before and after applying Cordran to avoid spreading the medication to other areas of the body.
Side Effects of Cordran
Common Side Effects
- Burning or stinging at the application site
- Skin dryness
- Itching
Uncommon/Severe Side Effects
- Skin thinning (atrophy)
- Stretch marks
- Adrenal suppression with long-term use
- Allergic reactions (rash, swelling, difficulty breathing)
Risks and Warnings of Cordran
- Skin Atrophy: Prolonged use of Cordran can lead to thinning of the skin, especially in sensitive areas such as the face or groin. Follow your healthcare provider’s guidance regarding the duration of use.
- Adrenal Suppression: Long-term use of topical corticosteroids like Cordran can suppress adrenal gland function, leading to systemic side effects such as fatigue and weight loss. This risk is higher when large areas of the body are treated or when occlusive dressings are used.
- Risk of Infection: Cordran can increase the risk of skin infections. If the skin becomes red, swollen, or painful, consult your healthcare provider immediately.
Interactions with Cordran
Common Drug Interactions
- Other Topical Corticosteroids: Using multiple corticosteroid products simultaneously can increase the risk of side effects, including skin thinning and systemic absorption.
- Occlusive Dressings: Using occlusive dressings over areas treated with Cordran can increase absorption of the medication, leading to a higher risk of side effects like adrenal suppression.
Alternatives to Cordran
- Hydrocortisone: A low-potency corticosteroid used for milder skin conditions such as mild eczema and dermatitis.
- Triamcinolone (Kenalog): A medium-potency corticosteroid for more severe inflammatory skin conditions.
- Betamethasone (Diprolene): A high-potency corticosteroid used for severe skin inflammation, often in cases of psoriasis.
