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Constulose
Constulose, medically known as Lactulose, is a type of medication classified as a synthetic sugar used to treat constipation and to prevent or treat certain complications of liver disease (hepatic encephalopathy). It works by causing water to be drawn into the colon, which in turn softens the stool and increases the number of bowel movements. Common side effects include bloating, gas, and stomach cramps.
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Frequently Asked Questions
Can I take Constulose if I have diabetes?
Yes, but it contains sugar which may affect your glucose levels. Make sure you monitor your blood sugar regularly while on medication.
Does Constulose make you gassy?
Yes, bloating and flatulence are common side effects of Constulose. Talk to your doctor if these effects persist or worsen.
I missed a dose of Constulose, what should I do?
Take the missed dose as soon as you remember. Skip the missed dose if it's almost time for your next scheduled dose. Do not take an extra dose to make up for the missed dose.
What should I do if I take too much Constulose?
If you've taken too much Constulose, you may experience severe diarrhea. Contact your doctor or seek emergency medical attention.
Comprehensive Drug Guide
How Does Constulose Work?
Constulose is a synthetic disaccharide that is broken down in the colon into products that pull water out from the body and into the colon to soften stools and produce a laxative effect. It also helps reduce the amount of ammonia in the blood.
What is Constulose Used For?
FDA indications: Constulose is used to treat chronic constipation and hepatic encephalopathy.
Offlabel uses: Occasionally it is used for diagnostic bowel preparation.
Common Dosages
Oral solution: 10 g/15 mL
Powder for oral solution: 10 g/packet
Typical Dosing
FDA Approved Indications
- Constipation: 15 mL (10 g) 14 times a day. The dose may be increased or decreased according to the patient's need.
- Hepatic encephalopathy: 3045 mL (2030 g) 34 times daily, this dosage can be adjusted as needed.
Off-Label Uses
- Diagnostic bowel preparation: Depends on individual patient needs and as instructed by a healthcare provider.
Who Shouldn't Take Constulose?
- If you require a lowgalactose diet.
- Have a blockage in your bowel (intestinal obstruction).
- Are on a lowlactose diet, as Constulose contains lactose.
- Have diabetes, as Constulose contains galactose and may affect your blood sugar levels.
Advice From The Pharmacist
- Constulose can be taken either with a meal or on an empty stomach.
- It might take up to 48 hours for you to have a bowel movement after you take the medication.
- Drink plenty of fluids while taking Constulose to prevent dehydration.
- Don't take more than 2 doses at one time to make up for a missed dose.
Side Effects of Constulose
Common Side Effects
- Bloating
- Gas
- Stomach cramps.
Uncommon/Severe Side Effects
- Uncommon side effects:
- Nausea
- Diarrhea
- Vomiting
- Rash
- Rare side effects:
- Irregular heartbeat due to electrolyte imbalance
- Muscle weakness due to electrolyte imbalance
- Severe stomach pain due to electrolyte imbalance
Risks and Warnings of Constulose
- Constulose can cause dehydration and electrolyte imbalance if it's taken in high doses or for a prolonged period.
- Be sure to drink plenty of fluids while you're taking this medication.
- Constulose is not recommended for patients who are on a lowgalactose diet.
- It should be used with caution in patients with diabetes due to its sugar content.
Interactions with Constulose
Common Drug Interactions
- Other laxatives
- Antacids
Alternatives to Constulose
- Docusate
- Bisacodyl
- Polyethylene Glycol
- Psyllium
