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Claravis
Claravis is a brand of isotretinoin, a powerful retinoid used to treat severe nodular acne that has not responded to other treatments. Isotretinoin works by decreasing the size of the sebaceous glands, reducing the amount of oil produced in the skin, and inhibiting the growth of acne-causing bacteria.
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Frequently Asked Questions
How long does it take for Claravis to work?
Claravis typically starts to show improvement within 1 to 2 months, but the full course of treatment usually lasts 4 to 6 months.
Can I take Claravis while pregnant?
No, Claravis must never be taken during pregnancy due to the risk of severe birth defects.
Can I drink alcohol while taking Claravis?
It's best to avoid alcohol, as it can increase the risk of liver damage and other side effects.
What should I do if I miss a dose?
If you miss a dose of Claravis, take it as soon as you remember. However, if it is close to the time of your next dose, skip the missed dose and resume your regular dosing schedule. Do not double up doses to make up for the missed one.
Can Claravis cure acne permanently?
Claravis can significantly improve or clear severe acne, and many patients experience long-term remission after completing a course of treatment. However, some individuals may require additional treatment courses or maintenance therapy.
Comprehensive Drug Guide
How Does Claravis Work?
Claravis reduces the production of sebum (skin oil), which helps prevent clogged pores and reduces acne-causing bacteria. It also has an anti-inflammatory effect on the skin, helping to reduce swelling and redness associated with severe acne.
Common Dosages
- 10 mg, 20 mg, 30 mg, and 40 mg.
Typical Dosing
- The typical dose is based on body weight, usually starting at 0.5 to 1 mg per kg of body weight per day, divided into two doses, taken with food. The treatment duration is typically 15 to 20 weeks.
Typical Dosing
FDA Approved Indications
- Severe nodular acne in patients who have not responded to other treatments.
Who Shouldn't Take Claravis?
- Pregnancy or planning to become pregnant (due to high risk of birth defects).
- Severe liver disease.
- Known hypersensitivity to isotretinoin or any of its ingredients.
Advice From The Pharmacist
- Female patients must use two forms of birth control and take monthly pregnancy tests due to the high risk of birth defects.
- Avoid excessive sun exposure while on Claravis, as it can make your skin more sensitive to sunlight.
- Do not donate blood during treatment and for at least one month after stopping the medication.
Side Effects of Claravis
Common Side Effects
- Dry skin
- Chapped lips
- Dry eyes
- Nosebleeds
Uncommon/Severe Side Effects
- Severe birth defects if taken during pregnancy
- Liver toxicity
- Increased risk of depression or mood changes
Risks and Warnings of Claravis
- Pregnancy warning: Isotretinoin can cause severe birth defects if taken during pregnancy. Female patients must adhere to strict birth control measures.
- Mental health: There is a potential risk of depression, anxiety, and suicidal thoughts associated with Claravis.
- Liver and lipid monitoring: Claravis can increase cholesterol and triglyceride levels, so regular blood tests are needed.
Interactions with Claravis
Common Drug Interactions
- Vitamin A supplements: Taking additional vitamin A can increase the risk of vitamin A toxicity.
- Tetracyclines: Combining Claravis with tetracyclines can increase the risk of increased pressure in the brain (pseudotumor cerebri).
Alternatives to Claravis
- Accutane (isotretinoin): A similar isotretinoin-based medication for severe acne.
- Topical retinoids: For milder cases of acne, products like tretinoin may be used.
- Oral antibiotics: Such as doxycycline or minocycline, for moderate acne.
