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BSS Plus

BSS Plus is a sterile, balanced salt solution used primarily during ophthalmic surgery, such as cataract surgery, corneal transplantation, and other intraocular procedures. It is designed to irrigate and maintain the natural conditions of the eye, keeping the tissues hydrated and providing a protective environment during surgical procedures.



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Frequently Asked Questions

Is BSS Plus safe for all types of eye surgery?
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BSS Plus is designed for use in various types of eye surgery, including cataract extraction and corneal transplantation. It is generally considered safe and effective when used by trained healthcare professionals.

How is BSS Plus different from regular saline solution?
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BSS Plus contains a balanced mix of electrolytes and other components, such as bicarbonate, dextrose, and glutathione, which are designed to mimic the natural environment of the eye. This makes it more suitable for intraocular use during surgery compared to regular saline, which lacks these additional components.

Can BSS Plus cause complications after surgery?
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Complications from BSS Plus itself are rare. Most postoperative issues are related to the surgery rather than the irrigating solution. However, it is crucial to follow all postoperative care instructions provided by your surgeon to minimize the risk of complications.

Is BSS Plus used in every eye surgery?
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BSS Plus or a similar balanced salt solution is commonly used in many types of eye surgeries to irrigate the eye and maintain the natural environment of the tissues. The specific solution used may vary depending on the procedure and the surgeon's preference.

Can BSS Plus be used outside of surgery?
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No, BSS Plus is intended for use during eye surgery by healthcare professionals. It is not intended for at-home use or for treating eye conditions outside of a surgical setting.

Comprehensive Drug Guide

How Does BSS Plus Work?

BSS Plus provides an isotonic solution that mimics the natural aqueous humor of the eye. It contains essential electrolytes, such as sodium, potassium, calcium, magnesium, and chloride, along with bicarbonate, dextrose, and glutathione. These components help to maintain the proper pH, osmolarity, and electrolyte balance in the eye during surgery, which is crucial for protecting delicate ocular tissues from damage and ensuring optimal surgical outcomes.

What is BSS Plus Used For?

Intraocular Irrigation: During ocular surgical procedures, including cataract extraction, corneal transplantation, and other intraocular surgeries, to maintain the natural condition and hydration of the eye.

Common Dosages

BSS Plus is available by prescription and is used under the guidance of a healthcare professional during surgical procedures. It is not classified as a controlled substance. BSS Plus is supplied as a sterile solution for intraocular irrigation.

Administration: BSS Plus is administered by the surgeon or healthcare professional during eye surgery. The solution is applied directly to the eye using an irrigation system that delivers a steady flow of the solution to the ocular surface and intraocular spaces. The specific volume used depends on the type of procedure and the surgeon's preference.

Storage: BSS Plus should be stored at room temperature and used immediately after opening to maintain sterility.

Typical Dosing

FDA Approved Indications

The dosage of BSS Plus varies depending on the type and duration of the surgical procedure. It is used as needed to irrigate the eye throughout the surgery:

  • Typical Usage: BSS Plus is continuously or intermittently applied to the eye during surgery to keep the tissues hydrated and to flush out any debris or substances from the surgical field.


Who Shouldn't Take BSS Plus?

BSS Plus is contraindicated in patients with:

  • Known hypersensitivity to any of the components of the solution.
  • Situations where the product’s sterility cannot be assured, as it must be used in sterile conditions to avoid contamination and infection.


Advice From The Pharmacist

Patients undergoing surgery with BSS Plus should be aware that:

  • The solution is used exclusively in a surgical setting by trained professionals and is not for self-administration.
  • There are generally no aftercare instructions related to BSS Plus itself, but patients should follow their surgeon's postoperative care instructions carefully to ensure proper healing.
  • Any concerns or complications following surgery, such as unexpected eye pain, vision changes, or signs of infection, should be reported to the healthcare provider immediately.


Side Effects of BSS Plus

Common Side Effects

  • Intraocular Pressure Fluctuations: Temporary changes in intraocular pressure (IOP) during or after surgery.
  • Ocular Irritation: Mild irritation or discomfort following surgery, typically related to the procedure rather than the solution itself.
  • Contamination Risk: If the sterility of the solution is compromised, there is a risk of infection, though this is extremely rare when proper surgical protocols are followed.

Risks and Warnings of BSS Plus

Sterility: The primary risk associated with BSS Plus is the potential for contamination if the sterility of the solution is compromised. It is essential that the solution be handled in a sterile environment and used immediately after opening.

Postoperative Monitoring: Patients should be closely monitored after surgery for any signs of complications, such as increased intraocular pressure or infection, though these are generally related to the surgery itself rather than the use of BSS Plus.

Interactions with BSS Plus

Common Drug Interactions

There are no known drug interactions with BSS Plus when used as an intraocular irrigating solution during surgery. It is designed to be biocompatible with the tissues of the eye and is not expected to interact with other medications used in the perioperative setting.

Alternatives to BSS Plus

Alternative ophthalmic irrigating solutions include:

  • Balanced Salt Solution (BSS): A similar solution used for intraocular irrigation that does not contain additional nutrients like bicarbonate, dextrose, and glutathione.
  • Ringer's Lactate Solution: Sometimes used for irrigation in certain types of eye surgeries.
  • Custom-Mixed Solutions: Depending on the specific needs of the surgery and patient, a custom solution may be used.