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Bio Glo
Bio Glo is a brand of sterile fluorescein sodium ophthalmic strips used in eye examinations. Fluorescein sodium is a water-soluble dye that is applied to the eye to help healthcare professionals diagnose various ocular conditions. The dye highlights abnormalities on the corneal surface and can also be used to evaluate tear film stability, detect corneal abrasions, ulcers, or foreign bodies, and assess the fit of contact lenses.
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Frequently Asked Questions
How long does the yellow staining from Bio Glo last?
The yellow staining of the eye and surrounding skin typically resolves within a few hours as the dye is naturally flushed out of the body.
Can Bio Glo be used for contact lens wearers?
Yes, Bio Glo can be used for contact lens wearers, but the lenses should be removed before application and should not be reinserted until the dye has completely cleared from the eye to avoid staining.
Is Bio Glo safe for use in children?
Yes, Bio Glo is safe for use in children under the supervision of a healthcare provider. It is often used in pediatric eye examinations to detect corneal injuries or foreign bodies.
What should I do if I experience discomfort after using Bio Glo?
If you experience persistent discomfort, redness, or irritation after using Bio Glo, you should contact your healthcare provider. These symptoms may indicate an allergic reaction or irritation that needs to be addressed.
Can I drive after using Bio Glo?
It is recommended to wait until any temporary blurry vision caused by the dye has cleared before driving or operating machinery. This usually resolves within a few minutes after the examination.
Comprehensive Drug Guide
How Does Bio Glo Work?
When a Bio Glo strip is applied to the surface of the eye, the fluorescein sodium dye adheres to areas where there is a break in the corneal epithelium, such as abrasions or ulcers. Under a cobalt blue light, the dye fluoresces, or glows, highlighting these damaged areas. This fluorescence allows healthcare professionals to visualize and assess the extent of any damage to the cornea or tear film.
What is Bio Glo Used For?
Ophthalmic Examination: To detect corneal abrasions, ulcers, and foreign bodies.
Evaluation of Tear Film Stability: In the diagnosis of dry eye syndrome.
Contact Lens Fitting: To assess the fit and positioning of contact lenses on the eye.
Common Dosages
Bio Glo is available by prescription and over-the-counter for use by healthcare professionals. It is not classified as a controlled substance. The strips are typically available in single-use, sterile packaging.
Administration: The healthcare provider or technician will moisten the tip of a Bio Glo strip with a sterile saline solution and gently touch it to the lower conjunctiva of the eye. The patient is then asked to blink to spread the dye across the corneal surface. The eye is examined under a cobalt blue light to observe the fluorescein uptake and identify any abnormalities.
After Use: Any excess dye is typically flushed from the eye with sterile saline, and the strip is discarded.
Typical Dosing
FDA Approved Indications
The typical use of Bio Glo strips involves:
- Single Use: One strip per eye as needed for diagnostic purposes. The strip is applied to the lower conjunctival sac to introduce the dye into the eye.
Who Shouldn't Take Bio Glo?
Bio Glo is contraindicated in patients with:
- Known hypersensitivity or allergy to fluorescein sodium or any other component of the strips.
- Severe ocular infections or significant trauma where further irritation could be harmful.
Advice From The Pharmacist
Patients undergoing an eye examination with Bio Glo should be advised to:
- Inform their healthcare provider if they have a history of allergies to fluorescein or any other eye drops.
- Expect temporary yellow discoloration of the eye and surrounding skin, which will resolve within a few hours as the dye is flushed from the body.
- Avoid wearing contact lenses until the dye has been completely cleared from the eye, as it can stain the lenses.
- Report any persistent irritation, redness, or discomfort following the use of Bio Glo strips to their healthcare provider.
Side Effects of Bio Glo
Common Side Effects
- Temporary stinging or burning sensation upon application.
- Yellow discoloration of the eye or surrounding skin.
- Temporary blurry vision immediately after application.
Uncommon/Severe Side Effects
- Allergic Reactions: Such as redness, itching, or swelling of the eye, which requires discontinuation of use and medical attention.
Risks and Warnings of Bio Glo
Staining of Contact Lenses: Bio Glo can permanently stain contact lenses. Patients should be instructed to remove their lenses before the dye is applied and to wait until the dye is fully cleared from their eyes before reinserting the lenses.
Ocular Irritation: While rare, some patients may experience ocular irritation or an allergic reaction. In such cases, the use of the dye should be discontinued immediately.
Interactions with Bio Glo
Common Drug Interactions
Bio Glo is a diagnostic tool and does not have significant interactions with systemic medications. However, it is important to avoid using other ophthalmic products simultaneously to prevent interference with the dye’s effectiveness or to avoid excessive irritation.
Alternatives to Bio Glo
Alternative diagnostic tools for evaluating the cornea and tear film include:
- Rose Bengal Stain: Another dye used to detect damaged or devitalized cells on the surface of the eye.
- Lissamine Green: A dye that highlights dead or degenerated cells and mucus, used for dry eye diagnosis.
- Slit Lamp Examination: A non-invasive diagnostic method that allows detailed examination of the eye’s structures without the use of dyes.
The choice of diagnostic method depends on the specific clinical situation and the healthcare provider’s preference.
