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Beyaz
Beyaz is a combination oral contraceptive containing drospirenone (a progestin), ethinyl estradiol (an estrogen), and levomefolate calcium (a form of folate, vitamin B9). It is used primarily for preventing pregnancy by suppressing ovulation and altering the cervical mucus and uterine lining. In addition to contraception, Beyaz is also prescribed for treating premenstrual dysphoric disorder (PMDD), acne in women at least 14 years old, and improving folate levels to reduce the risk of neural tube defects should pregnancy occur.
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Frequently Asked Questions
How effective is Beyaz in preventing pregnancy?
When taken correctly, Beyaz is over 99% effective in preventing pregnancy. However, its effectiveness may decrease if pills are missed or taken inconsistently.
Can Beyaz help with acne?
Yes, Beyaz is approved for treating mild to moderate acne in women aged 14 and older who also wish to use oral contraception.
What should I do if I miss a dose of Beyaz?
If you miss one active pill, take it as soon as you remember and continue your regular dosing schedule. If you miss two or more pills, follow the instructions in the package insert and use backup contraception.
Can I take Beyaz if I smoke?
Smoking increases the risk of serious cardiovascular side effects from oral contraceptives, particularly in women over the age of 35. If you smoke, discuss alternative forms of contraception with your healthcare provider.
Does Beyaz contain a folate supplement?
Yes, Beyaz contains levomefolate calcium, which helps maintain folate levels to reduce the risk of neural tube defects in the event of pregnancy.
Comprehensive Drug Guide
How Does Beyaz Work?
- Inhibiting ovulation: Drospirenone and ethinyl estradiol prevent the release of an egg from the ovaries.
- Altering cervical mucus: The hormone changes make it harder for sperm to enter the uterus.
- Thinning the uterine lining: Beyaz makes the lining of the uterus less suitable for a fertilized egg to implant.
Common Dosages
- Tablets: 3 mg of drospirenone, 0.02 mg of ethinyl estradiol, and 0.451 mg of levomefolate calcium.
Typical Dosing
- Take one active tablet daily for 24 days, followed by one placebo tablet for 4 days.
- It is important to take Beyaz at the same time each day to maintain its effectiveness.
Typical Dosing
FDA Approved Indications
- Prevention of pregnancy
- Treatment of premenstrual dysphoric disorder (PMDD)
- Acne treatment in females aged 14 and older
- Folate supplementation to reduce the risk of neural tube defects
Who Shouldn't Take Beyaz?
- History of blood clots, stroke, or heart attack
- Uncontrolled high blood pressure
- Kidney, liver, or adrenal disease
- Known or suspected breast cancer or other estrogen-dependent cancers
- Smokers over the age of 35, as it increases the risk of cardiovascular events
Advice From The Pharmacist
- Take Beyaz at the same time every day to ensure effectiveness. Missing doses may reduce its efficacy, increasing the risk of pregnancy.
- If you miss a pill, follow the instructions on what to do based on how many pills were missed. Use backup contraception (e.g., condoms) if needed.
- Beyaz does not protect against sexually transmitted infections (STIs), so additional protection may be required.
Side Effects of Beyaz
Common Side Effects
- Nausea
- Breast tenderness
- Headache
- Mood changes
- Weight gain
Uncommon/Severe Side Effects
- Blood clots (deep vein thrombosis, pulmonary embolism)
- Stroke or heart attack
- Liver problems (jaundice, liver tumors)
- Severe allergic reactions (swelling, rash, difficulty breathing)
Risks and Warnings of Beyaz
- Increased cardiovascular risk: Smoking increases the risk of serious cardiovascular side effects from Beyaz, particularly in women over 35 years of age.
- Blood clot risk: The drospirenone component may increase the risk of deep vein thrombosis, pulmonary embolism, stroke, or heart attack.
- Liver disease: Beyaz is contraindicated in patients with liver disease or liver tumors.
- Hyperkalemia: Drospirenone may increase potassium levels, particularly in women with kidney or adrenal conditions.
Interactions with Beyaz
Common Drug Interactions
- Antibiotics: Some antibiotics, like rifampin, may reduce the effectiveness of Beyaz.
- Anticonvulsants: Medications such as carbamazepine and phenytoin may decrease the effectiveness of Beyaz.
- Potassium-sparing diuretics: Drospirenone may increase potassium levels, so use caution when combining with other medications that raise potassium, such as spironolactone.
Alternatives to Beyaz
- Yaz: Similar to Beyaz but without the added folate supplement.
- Lo Loestrin Fe: A low-dose combination oral contraceptive.
- NuvaRing: A vaginal ring that delivers hormones for contraception.
- Depo-Provera: A progestin-only injectable contraceptive given every three months.
