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Avita
Avita (tretinoin) is a topical retinoid medication primarily used to treat acne vulgaris. It is a derivative of vitamin A and works by promoting skin cell turnover, helping to reduce the formation of pimples, blackheads, and whiteheads. In addition to acne treatment, tretinoin is sometimes used off-label to reduce the appearance of fine wrinkles and improve skin texture. Avita is available in gel and cream formulations.
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Frequently Asked Questions
How long does it take for Avita to start working?
It may take 6 to 12 weeks of consistent use before noticeable improvements in acne are seen. It is important to continue using the medication as directed, even if there is an initial flare-up.
Can I use moisturizer with Avita?
Yes, using a gentle, non-comedogenic moisturizer can help alleviate dryness and irritation associated with Avita. Apply the moisturizer after the tretinoin has been absorbed.
What should I do if I experience severe irritation while using Avita?
If severe irritation occurs, reduce the frequency of application (e.g., every other day) or stop using the medication and consult your healthcare provider for further guidance.
Is Avita safe for long-term use?
Yes, Avita is generally considered safe for long-term use under the supervision of a healthcare provider. Regular use helps maintain improvements in acne over time.
Can I use Avita if I’m pregnant?
Avita is generally not recommended during pregnancy due to the potential risk to the fetus. Always consult your healthcare provider before using any medication during pregnancy.
Comprehensive Drug Guide
How Does Avita Work?
Avita works by increasing the rate of skin cell turnover. This process helps to prevent the clogging of hair follicles by encouraging the shedding of dead skin cells, which reduces the formation of comedones (blackheads and whiteheads). Over time, Avita can improve the appearance of acne and prevent new lesions from forming.
Common Dosages
- Topical gel: 0.025%, 0.05%, 0.1%
Typical Dosing
- Apply a pea-sized amount of Avita to the affected area once daily, preferably at bedtime.
- Gently wash and pat the skin dry before application. Avoid excessive use, as it can lead to increased irritation.
Typical Dosing
FDA Approved Indications
- Treatment of acne vulgaris
Who Shouldn't Take Avita?
- Known hypersensitivity to tretinoin or any components of the formulation
- Severe skin irritation or eczema, as it may worsen these conditions
Advice From The Pharmacist
- Use Avita as directed by your healthcare provider. It may take several weeks to notice improvement, and acne may appear worse before it gets better as the medication accelerates skin turnover.
- Avoid excessive sun exposure, as Avita can increase your skin's sensitivity to the sun. Use sunscreen daily and wear protective clothing when outdoors.
- Do not apply Avita to sunburned or irritated skin.
- Avoid using other topical products that may cause skin irritation, such as astringents, exfoliants, or harsh soaps, while using Avita.
Side Effects of Avita
Common Side Effects
- Redness
- Peeling
- Dryness
- Burning or stinging sensation
- Increased sensitivity to sunlight
Uncommon/Severe Side Effects
- Severe skin irritation
- Allergic reactions (swelling, rash, difficulty breathing)
Risks and Warnings of Avita
- Photosensitivity: Avita can make the skin more sensitive to sunlight, increasing the risk of sunburn. Patients should use sunscreen and avoid prolonged sun exposure while using this medication.
- Initial acne flare-up: In the first few weeks of use, acne may worsen as tretinoin begins to work. This is a normal part of the treatment process and typically improves with continued use.
- Skin irritation: Avoid using Avita on broken, sunburned, or irritated skin, as it may cause further irritation.
Interactions with Avita
Common Drug Interactions
- Other topical acne treatments: Using Avita with products containing benzoyl peroxide or salicylic acid may cause excessive dryness and irritation. If needed, these products should be applied at different times of day.
- Astringents and exfoliants: These products may increase skin irritation when used with Avita.
- Photosensitizing medications: Drugs that increase sensitivity to sunlight (e.g., tetracyclines) should be used cautiously with Avita, as they may increase the risk of skin damage from the sun.
Alternatives to Avita
- Differin (adapalene): Another topical retinoid used to treat acne, available over-the-counter in lower strengths.
- Retin-A (tretinoin): A similar formulation of tretinoin available for the treatment of acne and wrinkles.
- Benzoyl Peroxide: A topical antibacterial treatment for acne, often used in combination with retinoids.
- Clindamycin topical: An antibiotic used to treat acne, often in combination with topical retinoids or benzoyl peroxide.
