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Amvisc
Amvisc (generic name: sodium hyaluronate) is a viscoelastic solution used as a lubricant and cushion in ophthalmic surgeries, such as cataract extraction and intraocular lens (IOL) implantation. It is used to maintain the shape of the eye during surgery, protect delicate tissues, and facilitate surgical procedures. Sodium hyaluronate, the active ingredient in Amvisc, is a natural substance found in the body’s connective tissues and fluids, including the eyes.
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Frequently Asked Questions
How long does Amvisc stay in the eye after surgery?
Amvisc is typically removed from the eye at the end of the surgery to prevent any post-operative complications, such as increased intraocular pressure. However, small amounts may remain and will be naturally absorbed by the eye within a few days.
Can Amvisc cause vision problems after surgery?
Temporary blurring of vision may occur immediately after surgery, but this usually resolves within a few hours to days as the eye heals. If vision problems persist, contact your healthcare provider.
What is the purpose of using Amvisc during cataract surgery?
Amvisc helps protect delicate eye tissues, maintains space in the eye, and provides a clear surgical field during cataract extraction and lens implantation, reducing the risk of trauma and complications during the procedure.
Are there any risks of infection with Amvisc?
While the risk of infection is low with proper surgical technique, any ophthalmic procedure carries a small risk of infection. It’s important to follow post-operative care instructions and contact your healthcare provider if you notice signs of infection, such as redness, swelling, or pain.
Is Amvisc safe for people with glaucoma?
Amvisc can cause a temporary increase in intraocular pressure, so patients with glaucoma should be monitored closely after surgery to ensure that their eye pressure remains within a safe range.
Comprehensive Drug Guide
How Does Amvisc Work?
Amvisc works by mimicking the natural hyaluronic acid found in the eye, providing viscosity and elasticity to maintain space within the anterior chamber during surgery. This helps protect the corneal endothelium, stabilize the intraocular structures, and create a clear surgical field. Additionally, it helps keep tissues hydrated and cushioned, which reduces the risk of trauma to the eye during the procedure.
Common Dosages
- Sterile pre-filled syringes containing 1% sodium hyaluronate, typically 0.5 mL to 1.0 mL per syringe.
Typical Dosing
- Amvisc is administered directly into the anterior chamber of the eye by a healthcare professional during surgery. The exact dosage depends on the type of surgery being performed and the specific needs of the patient.
Typical Dosing
FDA Approved Indications
- Use as a viscoelastic agent during cataract extraction, intraocular lens implantation, corneal transplantation, glaucoma filtration surgery, and other ophthalmic procedures.
Who Shouldn't Take Amvisc?
- Known hypersensitivity to sodium hyaluronate or any of the components in the formulation.
- Active ocular infections or other conditions that may increase the risk of complications during surgery.
Advice From The Pharmacist
- Amvisc is used exclusively by healthcare providers during ophthalmic surgeries, so there are no at-home use instructions.
- Patients undergoing surgery should inform their healthcare provider of any eye conditions or infections before the procedure.
- Following surgery, adhere to your healthcare provider’s post-operative care instructions to promote healing and avoid complications such as infection or inflammation.
Side Effects of Amvisc
Common Side Effects
- Temporary increased intraocular pressure (IOP)
- Mild inflammation or redness in the eye
- Temporary blurring of vision following surgery
Uncommon/Severe Side Effects
- Corneal decompensation
- Increased intraocular pressure leading to glaucoma
- Infection
Risks and Warnings of Amvisc
- Increased Intraocular Pressure (IOP): Use of Amvisc can lead to temporary elevation in intraocular pressure. Patients with a history of glaucoma or other eye conditions that affect pressure should be closely monitored post-operatively.
- Corneal Damage: In rare cases, excessive use or improper removal of Amvisc can cause corneal damage. Surgeons must carefully remove the product after the procedure.
Interactions with Amvisc
Common Drug Interactions
No significant drug interactions have been identified with Amvisc. However, patients should inform their healthcare providers of any medications or supplements they are taking to avoid potential complications during surgery.
Alternatives to Amvisc
- Healon (sodium hyaluronate): Another commonly used viscoelastic agent for ophthalmic surgeries.
- Viscoat (sodium hyaluronate and chondroitin sulfate): A viscoelastic agent that provides additional protection to the corneal endothelium.
- Provisc: Another sodium hyaluronate-based viscoelastic solution used during eye surgeries.