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Afluria Quadrivalent
Afluria is an inactivated influenza vaccine designed to protect against the seasonal flu. It contains inactivated (killed) influenza viruses that stimulate the immune system to produce antibodies, helping the body fight off future infections. Afluria is typically updated each year to match the strains of flu virus that are predicted to circulate during the upcoming flu season. The vaccine is recommended for both children and adults to reduce the risk of getting the flu and its potentially severe complications, such as pneumonia, hospitalization, or death.
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Frequently Asked Questions
Can the flu vaccine give me the flu?
No, the virus in the flu vaccine is inactivated (killed) and cannot cause the flu. You may experience mild side effects, such as soreness at the injection site or a low-grade fever, but these are not signs of the flu.
How long does it take for the flu vaccine to work?
It takes about two weeks for your body to develop immunity after receiving the flu vaccine, so it’s important to get vaccinated before flu season starts.
Do I need a flu shot every year?
Yes, the flu virus changes every year, and the vaccine is updated to match the circulating strains. Annual vaccination is the best way to protect yourself from the flu.
Is Afluria safe for pregnant women?
Yes, the flu vaccine, including Afluria, is safe for pregnant women and is recommended to protect both the mother and the baby from flu-related complications.
What should I do if I miss getting vaccinated before flu season?
You can still get the flu shot even after the flu season starts. It’s never too late, as flu viruses can circulate well into the winter and early spring.
Comprehensive Drug Guide
How Does Afluria Quadrivalent Work?
Afluria works by exposing the immune system to inactivated influenza virus proteins. These proteins stimulate the immune system to produce antibodies, which can recognize and neutralize the actual flu virus if exposed. Since the virus in the vaccine is inactivated, it cannot cause the flu. The body typically takes about two weeks to build immunity after receiving the vaccine, and this protection lasts throughout the flu season.
Common Dosages
- Afluria Quadrivalent: Protects against four strains of the influenza virus (two A strains and two B strains).
- Afluria Trivalent: Protects against three strains of the influenza virus (two A strains and one B strain).
Typical Dosing
- 0.5 mL for individuals aged 3 years and older.
- 0.25 mL for children aged 6 months to 35 months (specific formulations may vary).
- For influenza prevention: A single dose of Afluria Quadrivalent is administered annually, ideally before the flu season begins (typically in the fall).
Typical Dosing
FDA Approved Indications
- Prevention of influenza (flu) in individuals 6 months of age and older.
- It is typically administered once a year before or during the flu season, which runs from fall through spring.
Who Shouldn't Take Afluria Quadrivalent?
- Severe allergic reaction (anaphylaxis) to a previous flu vaccine or any component of the vaccine (such as eggs, for certain formulations).
- Individuals with a known allergy to egg protein, as some flu vaccines are grown in eggs. However, some formulations of Afluria are egg-free.
Advice From The Pharmacist
- Afluria is most effective when administered before the start of flu season, typically in the fall.
- It is important to get vaccinated each year, as flu strains change, and the vaccine is updated annually.
- The flu shot cannot cause the flu, as the virus in the vaccine is inactivated.
- Mild side effects, such as soreness at the injection site, low-grade fever, or fatigue, may occur, but these are temporary and usually resolve within a day or two.
- The vaccine is safe for most individuals, including children, pregnant women, and older adults, but always consult your healthcare provider before getting vaccinated.
Side Effects of Afluria Quadrivalent
Common Side Effects
- Soreness, redness, or swelling at the injection site
- Low-grade fever
- Headache or muscle aches
- Fatigue
Uncommon/Severe Side Effects
- Severe allergic reactions (such as difficulty breathing, swelling of the face or throat)
- Guillain-Barré Syndrome (GBS), a rare disorder affecting the nerves
Risks and Warnings of Afluria Quadrivalent
- Vaccination Timing: It’s important to get vaccinated before flu season starts for optimal protection.
- Immune Response: Individuals with weakened immune systems or those receiving immunosuppressive therapy may have a reduced response to the vaccine.
Interactions with Afluria Quadrivalent
Common Drug Interactions
- Immunosuppressive medications (such as corticosteroids or chemotherapy), which may reduce the effectiveness of the vaccine.
- Other vaccines: You may receive other vaccines at the same time as Afluria, but talk to your healthcare provider if you are scheduled for multiple vaccinations.
Alternatives to Afluria Quadrivalent
- Other flu vaccines: Other formulations of the influenza vaccine are available, including trivalent and live attenuated influenza vaccines, which may be suitable based on individual health needs and preferences.
