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Afirmelle
Afirmelle is a combination oral contraceptive that contains ethinyl estradiol and desogestrel. It is primarily used for the prevention of pregnancy and helps regulate the menstrual cycle. Afirmelle works by preventing ovulation, thickening the cervical mucus to block sperm, and thinning the uterine lining to prevent implantation. This medication is effective in managing various menstrual-related conditions and offers additional benefits such as reduced menstrual cramps and lighter periods.
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Frequently Asked Questions
How long does it take for Afirmelle to become effective?
Afirmelle is generally effective after 7 days of consistent use. For immediate protection, it is advisable to use backup contraception during this period.
What should I do if I miss a dose of Afirmelle?
If you miss a dose, take it as soon as you remember. If it's close to the time for your next dose, skip the missed dose and continue with your regular schedule. Follow the instructions provided for missed doses to ensure continued effectiveness.
Can I use Afirmelle while breastfeeding?
Afirmelle is not typically recommended for breastfeeding women, as estrogen may affect milk production. Consult your healthcare provider for alternatives if you are breastfeeding.
Will Afirmelle affect my weight?
Weight changes can occur with hormonal contraceptives, but individual responses vary. It's important to discuss any concerns with your healthcare provider.
Can I get pregnant while using Afirmelle?
When taken correctly, Afirmelle is highly effective in preventing pregnancy. However, no contraceptive method is 100% effective. If you suspect pregnancy, consult your healthcare provider immediately.
Comprehensive Drug Guide
How Does Afirmelle Work?
Afirmelle functions by combining two hormones: ethinyl estradiol (an estrogen) and desogestrel (a progestin). This combination inhibits the body's natural hormonal cycle, preventing the release of an egg (ovulation). It also increases the viscosity of cervical mucus, making it difficult for sperm to enter the uterus, and alters the endometrial lining, reducing the likelihood of implantation should fertilization occur.
Common Dosages
- Tablets: 0.15 mg desogestrel and 0.02 mg ethinyl estradiol
Typical Dosing
- The recommended dosing regimen is one tablet taken orally once daily at the same time every day. The treatment cycle usually consists of 21 active pills followed by a 7-day break or placebo pills.
Typical Dosing
FDA Approved Indications
- Prevention of pregnancy in women of reproductive age
Who Shouldn't Take Afirmelle?
- Known hypersensitivity to ethinyl estradiol, desogestrel, or any components of the formulation
- History of thromboembolic disorders (e.g., deep vein thrombosis, pulmonary embolism)
- Certain types of cancers (e.g., breast cancer or hormone-sensitive tumors)
- Uncontrolled hypertension
Advice From The Pharmacist
- Take Afirmelle exactly as prescribed, and do not skip doses to maintain contraceptive efficacy.
- If a dose is missed, follow the instructions provided by your healthcare provider regarding missed pills.
- Be aware of potential side effects, such as nausea or breast tenderness, particularly when starting the medication.
- Regular follow-up appointments with your healthcare provider are important to monitor for any adverse effects or complications.
Side Effects of Afirmelle
Common Side Effects
- Nausea
- Headache
- Breast tenderness
- Mood changes
Uncommon/Severe Side Effects
- Blood clots (deep vein thrombosis or pulmonary embolism)
- Severe allergic reactions (e.g., rash, itching, swelling)
- Liver dysfunction
Risks and Warnings of Afirmelle
- Thromboembolic Events: Women using combination oral contraceptives are at an increased risk of blood clots. This risk is higher in smokers and those with other risk factors.
- Monitoring: Regular monitoring of blood pressure and other health parameters is recommended during use.
- Cancer Risk: Long-term use of oral contraceptives may have implications for breast and cervical cancer risk; patients should discuss their personal and family medical history with their healthcare provider.
Interactions with Afirmelle
Common Drug Interactions
- Antibiotics: Some antibiotics may reduce the effectiveness of hormonal contraceptives; consult your healthcare provider for guidance if antibiotics are needed.
- Anticonvulsants and Antiretrovirals: Certain medications can affect the metabolism of Afirmelle, potentially leading to decreased efficacy.
Alternatives to Afirmelle
- Other hormonal contraceptives: Such as different combination oral contraceptives, progestin-only pills, or hormonal IUDs.
- Barrier methods: Including condoms or diaphragms.
- Long-acting reversible contraceptives (LARCs): Such as implants or IUDs that do not require daily attention.
