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ActHIB

ActHIB is a vaccine that provides protection against Haemophilus influenzae type b (Hib), a bacterium that can cause serious infections, particularly in children under five years of age. Hib infections can lead to severe conditions such as meningitis, pneumonia, and epiglottitis. The vaccine helps the body develop immunity to this bacterium, significantly reducing the risk of Hib-related diseases.



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Frequently Asked Questions

Is ActHIB safe for my child?
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Yes, ActHIB is considered safe and effective for preventing Hib infections in children. Side effects are generally mild and temporary.

What should I do if my child misses a dose of ActHIB?
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If your child misses a dose, consult your healthcare provider for guidance on rescheduling the vaccination.

Can ActHIB cause any serious side effects?
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Serious side effects are rare, but parents should watch for signs of an allergic reaction and seek immediate medical attention if they occur.

How long does immunity from ActHIB last?
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Immunity from the ActHIB vaccine is expected to last for several years, but booster doses are recommended to maintain protection.

Can my child receive ActHIB if they are sick?
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If your child has a mild illness (e.g., a cold), they can usually receive the vaccine. However, consult your healthcare provider if your child has a more serious illness.

Comprehensive Drug Guide

How Does ActHIB Work?

ActHIB works by introducing a small, inactivated portion of the Hib bacterium (polysaccharide capsule) into the body. This exposure stimulates the immune system to produce antibodies against Hib, providing protection against future infections. The vaccine promotes the formation of memory cells that will recognize and fight the bacterium if exposed in the future.



Common Dosages

  • For infants and children: 0.5 mL intramuscularly, with a series of doses given at ages 2, 4, 6, and 12-15 months.

Typical Dosing

  • The recommended dosing schedule for ActHIB is as follows:
  • First dose: at 2 months
  • Second dose: at 4 months
  • Third dose: at 6 months
  • Booster dose: at 12-15 months


Typical Dosing

FDA Approved Indications

  • Prevention of invasive disease caused by Haemophilus influenzae type b in children.


Who Shouldn't Take ActHIB?

  • Known hypersensitivity to ActHIB or any components of the formulation
  • Severe allergic reactions to any vaccine component, including a previous dose of Hib vaccine


Advice From The Pharmacist

  • Ensure that the child is up to date with their vaccinations, as ActHIB is part of the recommended immunization schedule.
  • Monitor for any immediate allergic reactions after vaccination, although these are rare.
  • Discuss any concerns regarding vaccination schedules or potential side effects with your healthcare provider.


Side Effects of ActHIB

Common Side Effects

  • Redness, swelling, or tenderness at the injection site
  • Fever
  • Irritability
  • Fatigue


Uncommon/Severe Side Effects

  • Severe allergic reactions (e.g., rash, itching, swelling, or difficulty breathing)

Risks and Warnings of ActHIB

  • Allergic Reactions: Parents and caregivers should be aware of the potential for severe allergic reactions and seek immediate medical attention if they occur.
  • Monitoring: Children should be monitored for a short time after vaccination to observe for any adverse reactions.


Interactions with ActHIB

Common Drug Interactions

  • Other Vaccines: ActHIB can be administered concurrently with other vaccines, but it is important to follow the vaccination schedule recommended by healthcare providers.


Alternatives to ActHIB

  • Other Hib vaccines: There are other brands and formulations of the Hib vaccine available, which may be used based on specific vaccination schedules or guidelines.
  • Prophylactic antibiotics: In some cases, children at high risk for Hib disease may be given antibiotics as a preventive measure, although vaccination remains the primary method of prevention.